Roux C, Bull S, Goulding J, Lennard C
Department of Chemistry, Materials and Forensic Science, University of Technology, Sydney, NSW, Australia.
J Forensic Sci. 2000 Jan;45(1):99-114.
Common plastic drug packaging material available in Australia and in Asia was analyzed using a standard protocol including optical examination, UV-visible and Fourier transform infrared spectrometry. The aims were to determine whether there are significant differences between different sources, to establish the evidential value of these examinations, and to build a database of common packaging material. Visual examination was the most effective means for discriminating samples. Thickness and weight measurements provided useful information. Visualization of machining marks using crossed polarized light was found to be useful in the comparison process. UV-visible spectrophotometry has some value for distinguishing samples. Fourier transform infrared analysis was a good technique for determination of the polymer composition of the packaging. Significant differences were observed between Australian and overseas samples. The "Australian Database of Drug Packaging Materials" was created to systematically collate all of the collected data for application on personal computers. It is concluded that the properties of plastic packaging materials can be excellent indicators for identifying the specfic brand or origin of the packaging.
使用包括光学检查、紫外可见光谱和傅里叶变换红外光谱在内的标准方案，对澳大利亚和亚洲现有的常见塑料药品包装材料进行了分析。目的是确定不同来源之间是否存在显著差异，确定这些检查的证据价值，并建立常见包装材料数据库。目视检查是区分样品的最有效手段。厚度和重量测量提供了有用信息。发现在比较过程中使用交叉偏振光观察加工痕迹很有用。紫外可见分光光度法在区分样品方面有一定价值。傅里叶变换红外分析是确定包装聚合物成分的良好技术。在澳大利亚和海外样品之间观察到显著差异。创建了“澳大利亚药品包装材料数据库”，以便系统整理所有收集的数据，供个人计算机使用。得出的结论是，塑料包装材料的特性可以成为识别包装特定品牌或产地的出色指标。
