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恶性淋巴瘤化疗后完全性房室传导阻滞消失:一例报告

Disappearance of complete atrioventricular block after chemotherapy for malignant lymphoma: a case report.

作者信息

Matsuo T, Nishiura R, Tsumori Y, Maeno M, Kumagae H, Imamura T, Koiwaya Y, Eto T, Nagamine H, Inoue S

机构信息

First Department of Internal Medicine, Miyazaki Medical College.

出版信息

J Cardiol. 1999 Dec;34(6):345-9.

PMID:10642932
Abstract

A 77-year-old man with malignant lymphoma presented with dizziness and exertional dyspnea. Physical examination revealed marked bradycardia (36 beats/min). Twelve-lead electrocardiography showed complete atrioventricular block with narrow QRS escape beats. Gallium scintigraphy demonstrated significant abnormal uptake in the heart. Transesophageal echocardiography showed a thick interatrial septum with increased echogenecity. He underwent chemotherapy under external temporary pacing with a suspected diagnosis of complete atrioventricular block secondary to cardiac invasion of malignant lymphoma. Atrioventricular conduction progressively improved and the complete atrioventricular block disappeared. He is currently well and has required no cardiac pacing for 6 months. We conclude that complete atrioventricular block may be reversible in some patients with malignant lymphoma, even in the elderly.

摘要

一名77岁的恶性淋巴瘤男性患者出现头晕和劳力性呼吸困难。体格检查发现显著心动过缓(36次/分钟)。十二导联心电图显示完全性房室传导阻滞伴窄QRS逸搏。镓闪烁扫描显示心脏有明显异常摄取。经食管超声心动图显示房间隔增厚,回声增强。他在临时体外起搏下接受化疗,疑似诊断为恶性淋巴瘤心脏浸润继发的完全性房室传导阻滞。房室传导逐渐改善,完全性房室传导阻滞消失。他目前情况良好,6个月来无需心脏起搏。我们得出结论,即使是老年患者,某些恶性淋巴瘤患者的完全性房室传导阻滞也可能是可逆的。

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Complete heart block and persistent lactic acidosis as an initial presentation of non-hodgkin lymphoma in a critically ill newly diagnosed AIDS patient.完全性心脏传导阻滞和持续性乳酸酸中毒作为一名新诊断为艾滋病的危重症患者非霍奇金淋巴瘤的初始表现。
Case Rep Crit Care. 2014;2014:214970. doi: 10.1155/2014/214970. Epub 2014 Nov 6.
2
A case of complete heart block reverting to normal sinus rhythm after treatment for cardiac invasive Burkitt's lymphoma.一例心脏侵袭性伯基特淋巴瘤治疗后完全性心脏传导阻滞恢复为正常窦性心律的病例。
Ann Hematol. 2007 Sep;86(9):687-90. doi: 10.1007/s00277-007-0290-x. Epub 2007 Apr 5.