[The colonization resistance of the mucous membrane of the large intestine in patients with rheumatoid arthritis in a period of exacerbation].

Specific and quantitative compositions of the colon mucous microflora in 36 patients with rheumatic arthritis (RA) in the remission period were studied. The mucous membrane of healthy people is colonized by bifidobacteria, lactobacilli, Bacteroides, Escherichia and enterococci. The mucous membrane in such people is mainly colonized by aerobic opportunistic conventionally pathogenic enterobacteria (enteropathogenic Escherichia, Citrobacter [correction of cytobacter], Enterobacter, Klebsiella, etc.), staphylococci, enterococci and anaerobic bacteria (Bacteroides, peptococci, peptostreptococci, etc.). Taking into account significant changes of colonization resistance in the colon mucous membrane in remission period of RA, it is necessary to apply bacteriotherapy, using bacterial drugs containing bifidobacteria and lactobacteria.