Aleksić P, Durović B, Raicević R
Clinic for Eye Diseases, Military Medical Academy, Belgrade.
Vojnosanit Pregl. 1999 Sep-Oct;56(5):471-5.
This paper deals with the experimental results of the effect of 1% dopamine on intraocular pressure, pupillary diameter and hemodynamic parameters after its local application in the rabbit eye. Our results show that locally applied dopamine caused an initial increase of intraocular pressure (IOP) (1 h), followed by its decrease that was the most pronounced 3 hours later. Mydriasis was an immediate effect of dopamine, which persisted until the end of the second hour. There were no changes in blood pressure and heart rate. Although the exact mechanism of dopamine effect on IOP is not known yet, our results point out that this is mainly due to the decrease fo aqueous humor formation.
本文探讨了1%多巴胺局部应用于兔眼后对眼压、瞳孔直径和血流动力学参数的影响的实验结果。我们的结果表明，局部应用多巴胺会使眼压（IOP）最初升高（1小时），随后降低，3小时后降低最为明显。散瞳是多巴胺的即时效应，持续到第二小时末。血压和心率没有变化。虽然多巴胺对眼压影响的确切机制尚不清楚，但我们的结果表明，这主要是由于房水生成减少所致。
