Oosterbaan R, Burns M J
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
J Emerg Med. 2000 Jan;18(1):55-9. doi: 10.1016/s0736-4679(99)00176-6.
Phenylpropanolamine is a sympathomimetic agent widely used in over-the-counter and prescription decongestant medications. We describe a young woman without cardiac risk factors who sustained myocardial infarction after unintentional overuse of a nasal decongestant containing phenylpropanolamine. The pathophysiology of myocardial injury and current management strategies as related to this agent are discussed. Although serious adverse reactions to phenylpropanolamine are uncommon, potentially serious harm may be caused by this widely available drug in healthy individuals.
苯丙醇胺是一种拟交感神经药，广泛用于非处方和处方减充血剂药物中。我们描述了一名无心脏危险因素的年轻女性，她在无意中过量使用含苯丙醇胺的滴鼻剂后发生了心肌梗死。本文讨论了与该药物相关的心肌损伤病理生理学及当前的管理策略。虽然苯丙醇胺严重不良反应并不常见，但这种广泛可得的药物可能会对健康个体造成潜在的严重伤害。
