Simmons E W, Barghi N, Muscott J R
J Dent Res. 1976 Jul-Aug;55(4):606-10. doi: 10.1177/00220345760550041001.
Both sealants experience early thermocyclic failure, which is manifested as marginal breakdown or separation. From the 20 to 70% failure range (Fig 5) Nuva Seal was three times as resistant to thermocyclic stressing as was Epoxylite 9075. That is, the Nuva Seal-sealed teeth had to be cycled three times more than the Epoxylite 9075-sealed teeth to effect the same failure rates. Both Epoxylite and Nuva Seal reach the same failure rate at 7,000 cycles (75% failure rate). Extremely careful visual examination is required to detect marginal separation failures of pit and fissure sealants.
两种封闭剂均出现早期热循环失败，表现为边缘破裂或分离。在20%至70%的失败率范围内（图5），Nuva Seal对热循环应力的耐受性是Epoxylite 9075的三倍。也就是说，用Nuva Seal封闭的牙齿要比用Epoxylite 9075封闭的牙齿多循环三次才能达到相同的失败率。Epoxylite和Nuva Seal在7000次循环时达到相同的失败率（75%的失败率）。需要极其仔细的目视检查才能检测到窝沟封闭剂的边缘分离失败情况。
