Kaipiainen-Seppänen O, Aho K
Department of Medicine, Kuopio University Hospital, Finland.
J Rheumatol. 2000 Jan;27(1):94-100.
To investigate trends in the incidence of chronic inflammatory joint diseases.
Subjects entitled to receive drug reimbursement for chronic inflammatory joint diseases in 5/21 central hospital districts (population base about 1 million adults) in Finland during 1995 were studied. The mean age at disease onset was compared with figures from 1975, 1980, 1985, and 1990. Incidence rates were compared with those from 1980, 1985, and 1990.
A total of 710 subjects were entitled to drug reimbursement for chronic inflammatory joint disease that had started at the age of 16 or over. The total incidence was 65/100,000 (95% confidence interval 60.7-70.4); the figures for rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis, and undifferentiated chronic poly/oligoarthritis were 34, 6, 7, and 13/100,000, respectively. In RA, the mean age at diagnosis was 59.0 years and was the same in rheumatoid factor (RF) positive and RF negative disease. The mean age at diagnosis had increased by 8.8 years from 1975 to 1995 (p<0.001). A 14% decline was evident in the incidence of RA in 1990 and 1995 compared with the earlier years (p = 0.013). In the younger age groups (35-54 years), the incidence declined by 50% compared with the year 1980. The incidence of spondyloarthropathies remained similar during 1980-95.
Continuous monitoring of sickness insurance data provides information on the epidemiology of inflammatory joint diseases that will be useful in assessing demand for and supply of health services.
调查慢性炎症性关节疾病的发病率趋势。
对1995年芬兰5个/21个中心医院辖区(约100万成年人口基数)中有权获得慢性炎症性关节疾病药物报销的受试者进行研究。将疾病发病时的平均年龄与1975年、1980年、1985年和1990年的数据进行比较。发病率与1980年、1985年和1990年的发病率进行比较。
共有710名受试者有权获得16岁及以上开始的慢性炎症性关节疾病的药物报销。总发病率为65/100,000(95%置信区间60.7 - 70.4);类风湿关节炎(RA)、强直性脊柱炎、银屑病关节炎和未分化慢性多/寡关节炎的发病率分别为34、6、7和13/100,000。在RA中,诊断时的平均年龄为59.0岁,类风湿因子(RF)阳性和RF阴性疾病相同。从1975年到1995年,诊断时的平均年龄增加了8.8岁(p<0.001)。与早期相比,1990年和1995年RA的发病率明显下降了14%(p = 0.013)。在较年轻的年龄组(35 - 54岁)中,与1980年相比发病率下降了50%。1980 - 1995年期间脊柱关节病的发病率保持相似。
持续监测疾病保险数据可提供有关炎症性关节疾病流行病学的信息,这将有助于评估卫生服务的需求和供应。