Kaipiainen-Seppanen O, Aho K, Heliovaara M
Department of Medicine, Kuopio University Hospital, Finland.
J Rheumatol. 1997 Mar;24(3):496-9.
To determine the incidence and prevalence of clinically significant ankylosing spondylitis (AS) in Finland.
The incidence study covered patients entitled under the nationwide sickness insurance scheme to receive specially reimbursed medication for AS in 5/21 central hospital districts in Finland (population base about one million adults > or = 16 years of age) in 1980, 1985, and 1990. The prevalence study covered a representative sample of the Finnish population > or = 30 years of age, initially comprising 8000 persons, of whom 7217 participated in the field survey carried out in 1978-1980.
The annual incidence of AS requiring antirheumatic medication was 6.9/100,000 [95% confidence interval (CI), 6.0-7.8] adults. Eleven cases of clinically significant AS were encountered in the prevalence study, corresponding to a prevalence of 0.15% (95% CI, 0.08-0.27%). The ratio between the prevalence rate and the annual incidence rate was 22.
This study provides population based data on the incidence and prevalence of clinically significant AS in Finland. The incidence rates of AS remained similar for the 3 study years.
确定芬兰临床显著型强直性脊柱炎（AS）的发病率和患病率。
发病率研究涵盖了1980年、1985年和1990年芬兰5/21个中央医院区中符合全国疾病保险计划规定、有权接受AS特殊报销药物治疗的患者（以约100万16岁及以上成年人作为人口基数）。患病率研究涵盖了芬兰30岁及以上具有代表性的人群样本，最初包括8000人，其中7217人参与了1978 - 1980年进行的实地调查。
需要抗风湿药物治疗的AS年发病率为每10万成年人中有6.9例[95%置信区间（CI），6.0 - 7.8]。在患病率研究中发现了11例临床显著型AS病例，患病率为0.15%（95% CI，0.08 - 0.27%）。患病率与年发病率之比为22。
本研究提供了基于人群的芬兰临床显著型AS发病率和患病率的数据。在这3个研究年份中，AS的发病率保持相似。
