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本文引用的文献

1
Measurement of Glucose Utilization by Pseudomonas fluorescens That Are Free-Living and That Are Attached to Surfaces.荧光假单胞菌的自由生活和附着表面时的葡萄糖利用率的测量。
Appl Environ Microbiol. 1986 Oct;52(4):672-6. doi: 10.1128/aem.52.4.672-676.1986.
2
Elastase activity of anaerobes isolated from amniotic fluid with preterm premature rupture of membranes.
Am J Obstet Gynecol. 1999 Feb;180(2 Pt 1):378-80. doi: 10.1016/s0002-9378(99)70217-6.
3
Role of Fusobacterium nucleatum and coaggregation in anaerobe survival in planktonic and biofilm oral microbial communities during aeration.具核梭杆菌及共聚作用在曝气过程中浮游和生物膜口腔微生物群落厌氧菌存活中的作用
Infect Immun. 1998 Oct;66(10):4729-32. doi: 10.1128/IAI.66.10.4729-4732.1998.
4
Complete nucleotide sequence of pSK41: evolution of staphylococcal conjugative multiresistance plasmids.pSK41的完整核苷酸序列：葡萄球菌接合性多耐药质粒的进化
J Bacteriol. 1998 Sep;180(17):4350-9. doi: 10.1128/JB.180.17.4350-4359.1998.
5
The bacteria of periodontal diseases.牙周疾病的细菌
Periodontol 2000. 1994 Jun;5:66-77. doi: 10.1111/j.1600-0757.1994.tb00019.x.
6
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.空位BLAST和位置特异性迭代BLAST：新一代蛋白质数据库搜索程序。
Nucleic Acids Res. 1997 Sep 1;25(17):3389-402. doi: 10.1093/nar/25.17.3389.
7
Cloning and expression of FomA, the major outer-membrane protein gene from Fusobacterium nucleatum T18.具核梭杆菌T18主要外膜蛋白基因FomA的克隆与表达
Arch Oral Biol. 1997 Jan;42(1):19-24. doi: 10.1016/s0003-9969(96)00105-7.
8
Taxonomy, biology, and periodontal aspects of Fusobacterium nucleatum.具核梭杆菌的分类学、生物学及牙周方面
Clin Microbiol Rev. 1996 Jan;9(1):55-71. doi: 10.1128/CMR.9.1.55.
9
Identification of the replication region of Lactobacillus acidophilus plasmid pLA103.
FEMS Microbiol Lett. 1995 Nov 1;133(1-2):127-30. doi: 10.1111/j.1574-6968.1995.tb07872.x.
10
Adhere today, here tomorrow: oral bacterial adherence.今日黏附于此，明日仍在：口腔细菌黏附
J Bacteriol. 1993 Jun;175(11):3247-52. doi: 10.1128/jb.175.11.3247-3252.1993.

具核梭杆菌的天然质粒：特性及其在遗传系统开发中的应用

Native plasmids of Fusobacterium nucleatum: characterization and use in development of genetic systems.

作者信息

Haake S K, Yoder S C, Attarian G, Podkaminer K

机构信息

Divisions of Associated Clinical Sciences, UCLA School of Dentistry, Los Angeles, California 90095-1668, USA.

出版信息

J Bacteriol. 2000 Feb;182(4):1176-80. doi: 10.1128/JB.182.4.1176-1180.2000.

DOI:10.1128/JB.182.4.1176-1180.2000
PMID:10648549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC94399/
Abstract

Three native plasmids of Fusobacterium nucleatum were characterized, including DNA sequence analysis of one plasmid, pFN1. A shuttle plasmid, pHS17, capable of transforming Escherichia coli and F. nucleatum ATCC 10953 was constructed with pFN1. pHS17 was stably maintained in the F. nucleatum transformants, and differences in the transformation efficiencies suggested the presence of a restriction-modification system in F. nucleatum.

摘要

对具核梭杆菌的三个天然质粒进行了表征，包括对一个质粒pFN1的DNA序列分析。用pFN1构建了一种能够转化大肠杆菌和具核梭杆菌ATCC 10953的穿梭质粒pHS17。pHS17在具核梭杆菌转化子中稳定维持，转化效率的差异表明具核梭杆菌中存在限制修饰系统。