食物对不同类型铁片吸收的影响。

Influence of food on the absorption from different types of iron tablets.

作者信息

Ekenved G, Arvidsson B, Sölvell L

出版信息

Scand J Haematol Suppl. 1976;28:79-88. doi: 10.1111/j.1600-0609.1976.tb00350.x.

DOI:10.1111/j.1600-0609.1976.tb00350.x

Abstract

The influence of a standardized breakfast meal on the absorption of iron from two types of iron tablets - rapidly-disintegrating and slow-release tablets - was studied in 24 healthy subjects, using a serum iron technique and whole-body counter measurements. The meal markedly reduced the absorption of iron from both types of tablets. An 8-fold reduction was found with the rapidly-disintegrating tablets and a 3-fold reduction with the slow-release tablets. Under fasting conditions the rapidly-disintegrating tablets were significantly better absorbed than the slow-release tablets, whereas the reverse was found when the tablets were given with the meal.

摘要

在24名健康受试者中，采用血清铁技术和全身计数器测量法，研究了标准化早餐对两种类型铁片（速崩片和缓释片）中铁吸收的影响。该餐显著降低了两种片剂中铁的吸收。速崩片的铁吸收降低了8倍，缓释片降低了3倍。在禁食条件下，速崩片的吸收明显优于缓释片，而当片剂与餐同服时，情况则相反。