Duncan J L, Cederbom G J, Champaign J L, Smetherman D H, King T A, Farr G H, Waring A N, Bolton J S, Fuhrman G M
Department of Surgery, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, Louisiana 70121, USA.
Am Surg. 2000 Jan;66(1):5-9; discussion 9-10.
Image-guided core-needle breast biopsy (IGCNBB) is widely used to evaluate patients with abnormal mammograms; however, information is limited regarding the reliability of a benign diagnosis. The goal of this study was to demonstrate that a benign diagnosis obtained by IGCNBB is accurate and amenable to mammographic surveillance. Records of all patients evaluated by IGCNBB from July 1993 through July 1996 were reviewed. Biopsies were classified as malignant, atypical, or benign. All benign cases were followed by surveillance mammography beginning 6 months after IGCNBB. Of the 1110 patients evaluated by IGCNBB during the study period, 855 revealed benign pathology. A total of 728 of the 855 patients (85%) complied with the recommendation for surveillance mammography. A total of 196 IGCNBBs were classified as malignant; 59 cases were classified as atypical. The atypical cases were excluded from the statistical analysis. Only two patients have demonstrated carcinoma after a benign IGCNBB during the 2-year minimum follow-up period. The sensitivity and specificity of a benign result were 100.0 and 98.9 per cent, respectively. A benign diagnosis obtained by IGCNBB is accurate and therefore amenable to mammographic surveillance. The results of this study support IGCNBB as the preferred method of evaluating women with abnormal mammograms.
影像引导下的乳腺粗针穿刺活检（IGCNBB）被广泛用于评估乳房X光检查异常的患者；然而，关于良性诊断的可靠性的信息有限。本研究的目的是证明通过IGCNBB获得的良性诊断是准确的，并且适合进行乳房X光监测。回顾了1993年7月至1996年7月期间所有接受IGCNBB评估的患者的记录。活检被分类为恶性、非典型或良性。所有良性病例在IGCNBB后6个月开始接受乳房X光监测。在研究期间接受IGCNBB评估的1110名患者中，855例显示良性病理。855例患者中有728例（85%）遵循了乳房X光监测的建议。共有196例IGCNBB被分类为恶性；59例被分类为非典型。非典型病例被排除在统计分析之外。在至少2年的随访期内，只有两名患者在IGCNBB诊断为良性后出现了癌症。良性结果的敏感性和特异性分别为100.0%和98.9%。通过IGCNBB获得的良性诊断是准确的，因此适合进行乳房X光监测。本研究结果支持将IGCNBB作为评估乳房X光检查异常女性的首选方法。
