Futei Y, Konohana I
Department of Dermatology, Hiratsuka City Hospital, Kanagawa 254-0065, Japan.
Br J Dermatol. 2000 Jan;142(1):116-9. doi: 10.1046/j.1365-2133.2000.03251.x.
We report a case of erythema elevatum diutinum (EED) in association with malignant B-cell lymphoma. A 62-year-old man developed EED with an unusual distribution involving the palms, soles and nails. Treatment with dapsone was effective for his skin and nails until he developed generalized lymphadenopathy which turned out to be malignant lymphoma. Many haematological diseases, e.g. IgA paraproteinaemia and myeloma, have been reported in association with EED, but not malignant lymphoma. Even though it may just be a coincidence, we would like to add malignant lymphoma as one of the diseases associated with EED because the activity of EED and malignant lymphoma fluctuated in parallel.
我们报告一例持久性隆起性红斑（EED）合并恶性B细胞淋巴瘤的病例。一名62岁男性患持久性隆起性红斑，其分布异常，累及手掌、足底和指甲。在他出现全身性淋巴结病并被诊断为恶性淋巴瘤之前，使用氨苯砜治疗其皮肤和指甲有效。许多血液系统疾病，如IgA副蛋白血症和骨髓瘤，已被报道与持久性隆起性红斑有关，但恶性淋巴瘤未见报道。尽管这可能只是巧合，但我们仍想将恶性淋巴瘤列为与持久性隆起性红斑相关的疾病之一，因为持久性隆起性红斑和恶性淋巴瘤的活动呈平行波动。
