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胎儿血红蛋白遗传性持续导致糖化血红蛋白假性升高。

Spurious elevation of hemoglobin A1c by hereditary persistence of fetal hemoglobin.

作者信息

Egede L E, Obah E, Lorch T, Oussova T

机构信息

Internal Medicine Residency Program, Greater Baltimore Medical Center, MD, USA.

出版信息

South Med J. 2000 Jan;93(1):62-4.

Abstract

We present the case of a 61- year-old black woman with a diagnosis of type 2 diabetes and a falsely elevated hemoglobin A1c (HbA1c) due to hereditary persistence of fetal hemoglobin. Physicians and allied health care professionals are alerted to this potentially significant problem in the diagnosis and management of diabetes mellitus (DM), particularly in the wake of the Diabetes Complications and Control Trial when "strict" glycemic control assessed by HbA1c is now the standard of care.

摘要

我们报告了一例61岁的黑人女性病例,该患者被诊断为2型糖尿病,由于胎儿血红蛋白遗传性持续存在,其糖化血红蛋白(HbA1c)出现假性升高。医生和相关医护人员应警惕糖尿病(DM)诊断和管理中这一潜在的重大问题,尤其是在糖尿病并发症控制试验之后,目前以HbA1c评估的“严格”血糖控制已成为护理标准。

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