Rasool A, Palevsky P M
Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA.
Am J Med Sci. 2000 Jan;319(1):25-37. doi: 10.1097/00000441-200001000-00003.
Generalized edema results from alterations in renal sodium homeostasis that ultimately result in an expansion of extracellular fluid volume and accumulation of interstitial fluid. The common edematous disorders include congestive heart failure, cirrhosis, nephrotic syndrome, and renal insufficiency. The abnormalities of sodium homeostasis contributing to edema formation in each condition are discussed. Management of volume homeostasis, with an emphasis on the role of diuretic therapy, is reviewed.
全身性水肿是由肾钠稳态改变引起的，最终导致细胞外液量增加和间质液积聚。常见的水肿性疾病包括充血性心力衰竭、肝硬化、肾病综合征和肾功能不全。本文讨论了每种情况下导致水肿形成的钠稳态异常。本文还回顾了容量稳态的管理，重点是利尿剂治疗的作用。
