弱磁场刺激对癫痫患者阵发性脑电波模式的影响。

Changes in paroxysmal brainwave patterns of epileptics by weak-field magnetic stimulation.

作者信息

Dobson J, St Pierre T, Wieser H G, Fuller M

机构信息

Department of Chemistry and UF Brain Institute, University of Florida, Gainesville 32611, USA.

出版信息

Bioelectromagnetics. 2000 Feb;21(2):94-9. doi: 10.1002/(sici)1521-186x(200002)21:2<94::aid-bem3>3.0.co;2-7.

DOI:10.1002/(sici)1521-186x(200002)21:2<94::aid-bem3>3.0.co;2-7

PMID:10653619

Abstract

In order to assess the effects of weak-field magnetic stimulation on brain electrical activity in epileptics, three patients suffering from mesial temporal lobe epilepsy (MTLE) were exposed to DC magnetic fields of 0.9 and 1.8 millitesla (mT). The EEG activity was recorded simultaneously from intracranial electrodes inserted through the foramen ovale (FO) and scalp electrodes. Significant enhancement of interictal epileptiform activity was observed in two patients, while in one patient, magnetic stimulation resulted in the cessation of interictal spike/wave trains.

摘要

为了评估弱磁场刺激对癫痫患者脑电活动的影响，三名患有内侧颞叶癫痫（MTLE）的患者暴露于0.9和1.8毫特斯拉（mT）的直流磁场中。通过卵圆孔（FO）插入的颅内电极和头皮电极同时记录脑电图活动。在两名患者中观察到发作间期癫痫样活动显著增强，而在一名患者中，磁刺激导致发作间期棘波/波群停止。