Dobson J, St Pierre T G, Schultheiss-Grassi P P, Wieser H G, Kuster N
Centre for Science and Technology in Medicine, Keele University, Thornburrow Drive, Hartshill, ST4 7QB, Stoke-on-Trent, UK.
Brain Res. 2000 Jun 23;868(2):386-91. doi: 10.1016/s0006-8993(00)02422-7.
Ten patients suffering from mesial temporal lobe epilepsy were exposed to weak, DC magnetic field stimulation following computer-controlled protocols established in previous studies. Poisson statistical analysis of the ten patients undergoing semi-invasive (foramen ovale) electrode monitoring reveals that for at least one experimental protocol, application of DC magnetic fields alters interictal epileptiform spike activity in five of ten patients. Similar results also have been observed in the analysis of both human and rat brains by employing weak, alternating magnetic field stimulation. Further study is necessary in order to optimize the magnetic field exposure protocol.
十名患有内侧颞叶癫痫的患者按照先前研究中建立的计算机控制方案，接受了弱直流磁场刺激。对十名接受半侵入性（卵圆孔）电极监测的患者进行的泊松统计分析显示，对于至少一种实验方案，施加直流磁场会改变十名患者中五名患者的发作间期癫痫样棘波活动。在对人和大鼠大脑进行弱交变磁场刺激的分析中也观察到了类似结果。为了优化磁场暴露方案，有必要进行进一步研究。
