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胸主动脉创伤性破裂的手术结果。

Surgical outcome of traumatic rupture of the thoracic aorta.

作者信息

Tatou E, Steinmetz E, Jazayeri S, Benhamiche B, Brenot R, David M

机构信息

Service de Chirurgie Cardio-Vasculaire, Hôpital du Bocage, Dijon, France.

出版信息

Ann Thorac Surg. 2000 Jan;69(1):70-3. doi: 10.1016/s0003-4975(99)01054-1.

Abstract

BACKGROUND

The aim of this study was to point out the results of different techniques of spinal cord protection in surgically-treated patients with traumatic thoracic aorta (TTA).

METHODS

A multicentric study was carried out involving 182 patients with TTA. Four patients died before surgery. Two patients were operated on without any investigation and 2 had no aortic tear at thoracotomy. The remaining 174 patients had aortic isthmus disruption and were included in the study. The mean age was 32.3+/-14.29 years with 126 men (72.4%) and 48 women (27.6%). Road accidents were causal in 163 patients (93.66%); polytraumatism was frequent. A standard chest roentgenogram led to a diagnosis which was confirmed with aortography in 94.8% of cases. Surgical repair of visceral lesions was performed in 52 patients (29.9%) for traumatic spleen, liver, diaphragm, mesentery, and gut. These operations were done before or after aortic operation in 21.3% and 8.6% of cases, respectively. Thirty-three patients (19%) died and 9 (5.2%) had paraplegia. Sixty-nine patients had clamp and sew technique (group 1). Ninety-three patients had different types of extracorporeal circulation (group 2), and 12 patients had Gott shunt (group 3). No difference appeared between the 3 groups according to mortality and paraplegia. But the sex ratio, age, visceral lesions, craniocerebral lesions, the type of aortic repair, and cross-clamp time were discriminative.

RESULTS

The univariate analysis point out age, cross-clamp time, hemothorax, and anatomical type of aortic injury as the risk factors of death. This was confirmed by a multivariable test which retained age, cross-clamp time, and hemothorax as risk factors. When not diagnosed in time, TTA is serious and has a bad prognosis. In spite of a high mortality and morbidity, the surgical management has improved. Immediate operation and medullar protection are the stumbling block in this operation.

CONCLUSIONS

Operation can be delayed in some cases, but one must take care of hemodynamic instability. This calls for a repair of the serious associated lesions first, or of a quick performing of a thoracotomy for ruptured aorta. The question remains, is it better to protect the spinal cord with the lower aortic perfusion and avoid the simple cross-clamp? Clinical studies give few answers to this question, and the best answer has not yet been given, as we lack prospective studies in this field.

摘要

背景

本研究的目的是指出在手术治疗创伤性胸主动脉(TTA)患者时不同脊髓保护技术的效果。

方法

开展了一项多中心研究,纳入182例TTA患者。4例患者在手术前死亡。2例患者未经任何检查即接受手术,2例在开胸手术时未发现主动脉撕裂。其余174例患者存在主动脉峡部破裂,被纳入研究。平均年龄为32.3±14.29岁,其中男性126例(72.4%),女性48例(27.6%)。163例患者(93.66%)的病因是道路交通事故;多发伤很常见。标准胸部X线片可做出诊断,94.8%的病例经主动脉造影得以证实。52例患者(29.9%)因创伤性脾、肝、膈肌、肠系膜和肠道损伤接受了内脏损伤的手术修复。这些手术分别在21.3%和8.6%的病例中在主动脉手术之前或之后进行。33例患者(19%)死亡,9例(5.2%)发生截瘫。69例患者采用钳夹缝合技术(第1组)。93例患者采用不同类型的体外循环(第2组),12例患者采用戈特分流术(第3组)。根据死亡率和截瘫情况,3组之间未出现差异。但性别比例、年龄、内脏损伤、颅脑损伤、主动脉修复类型和夹闭时间具有鉴别意义。

结果

单因素分析指出年龄、夹闭时间、血胸和主动脉损伤的解剖类型是死亡的危险因素。多变量检验证实了这一点,该检验确定年龄、夹闭时间和血胸为危险因素。TTA若未及时诊断则病情严重且预后不良。尽管死亡率和发病率较高,但手术治疗已有所改善。立即手术和脊髓保护是该手术的绊脚石。

结论

在某些情况下手术可以延迟,但必须注意血流动力学不稳定。这就需要首先修复严重的相关损伤,或者迅速对破裂的主动脉进行开胸手术。问题仍然存在,即采用较低的主动脉灌注保护脊髓并避免单纯夹闭是否更好?临床研究对此问题几乎没有给出答案,而且由于我们在该领域缺乏前瞻性研究,所以尚未给出最佳答案。

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