Kohno C
Department of Pediatrics, Hamamatsu Seirei General Hospital, Shizuoka.
No To Hattatsu. 2000 Jan;32(1):44-8.
We studied the P300 of two epileptic cases with almost continuous diffuse spike-wave discharges on sleep EEG: one with epilepsy with continuous spike-waves during slow wave sleep, and another with atypical benign partial epilepsy. These cases showed a marked prolongation of P300 latencies during nonconvulsive status epilepticus with continuous spike-waves during slow wave sleep. As they improved clinically and electroencephalographically, the latencies became normal. These findings indicate that P300 is a useful method to elucidate the pathophysiology of nonconvulsive status epilepticus with continuous spike-waves during slow wave sleep.
我们研究了两名睡眠脑电图上几乎持续出现弥漫性棘波-慢波放电的癫痫患者的P300：一名患有慢波睡眠期持续棘波的癫痫，另一名患有非典型良性部分性癫痫。这些病例在慢波睡眠期持续棘波的非惊厥性癫痫持续状态期间，P300潜伏期显著延长。随着他们临床和脑电图表现的改善，潜伏期恢复正常。这些发现表明，P300是阐明慢波睡眠期持续棘波的非惊厥性癫痫持续状态病理生理学的一种有用方法。
