Kobayashi K, Murakami N, Yoshinaga H, Enoki H, Ohtsuka Y, Ohtahara S
Department of Child Neurology, Okayama University Medical School, Japan.
Jpn J Psychiatry Neurol. 1988 Sep;42(3):509-14. doi: 10.1111/j.1440-1819.1988.tb01344.x.
On three epileptic conditions with common characteristics of almost continuous diffuse spike-and-wave discharges during sleep in EEG, clinical and electroencephalographic studies were undertaken to elucidate their pathophysiologies and interrelationships; namely on five cases of epilepsy with electrical status epilepticus during slow sleep (ESES), seven cases of a peculiar type of nonconvulsive status epilepticus in childhood (PNSE) and three cases of atypical benign partial epilepsy (ABPE). The dominant seizure types were absences and/or GTC in ESES, whereas they were focal motor seizures in PNSE and ABPE with more focalized epileptic discharges on EEGs than those in ESES. All the three conditions showed both features of generalized and partial epilepsies, although the former features were more prominent in ESES and the latter in PNSE and ABPE.
针对脑电图显示睡眠期间几乎持续出现弥漫性棘慢波放电这一共同特征的三种癫痫病症，开展了临床和脑电图研究，以阐明其病理生理学及相互关系；具体为五例慢波睡眠期癫痫性电持续状态（ESES）、七例儿童期特殊类型非惊厥性癫痫持续状态（PNSE）和三例非典型良性部分性癫痫（ABPE）。ESES的主要发作类型为失神发作和/或全身强直阵挛发作，而PNSE和ABPE的主要发作类型为局灶性运动发作，脑电图上的癫痫放电比ESES更局限。这三种病症均表现出全身性和部分性癫痫的特征，尽管全身性特征在ESES中更为突出，而部分性特征在PNSE和ABPE中更为突出。
