Loginov V I
Aviakosm Ekolog Med. 1999;33(6):12-6.
Histological, immunochemical and morphometric techniques were used to assess the functional activity of the thyroid parenchyma and calcitonin-producing C-cells of the thyroid gland (TG) in rats after 13 days on board Spacelab-2, in 5-6 hrs., and 14 days following the return from space flight. For the first time the fact of inhibition of the thyroid parenchyma and C-cells functioning during space flight was ascertained. Similarity of changes in the TG activity in and shortly after the space flight suggests that the morphological criteria used in 5 hrs. post flight give quite good insight into the character of changes occurring during microgravity. Two weeks of readaptation to the Earth's gravity result in recovery of the calcitonin production whereas the thyroid parenchyma displays postflight hyperactivity even after 14 days of return.
采用组织学、免疫化学和形态计量学技术，对大鼠在太空实验室-2上飞行13天、飞行后5 - 6小时以及返回太空飞行14天后甲状腺实质和甲状腺（TG）中产生降钙素的C细胞的功能活性进行评估。首次确定了太空飞行期间甲状腺实质和C细胞功能受到抑制这一事实。太空飞行期间及飞行后不久TG活性变化的相似性表明，飞行后5小时所采用的形态学标准能很好地洞察微重力期间发生的变化特征。两周的地球重力再适应导致降钙素产生恢复，而甲状腺实质在返回14天后仍表现出飞行后活性亢进。
