Plakhuta-Plakutina G I
Arkh Anat Gistol Embriol. 1979 Mar;76(3):17-21.
The investigation of the thyroid gland was carried out in Wistar rats, SPF colony 4.5--13 h and 25 days after a 18.5 days flight on board the space biosatellite "Cosmos-936". In animals subjected to weightlessness, moderate symptoms of the thyroid hypofunction were observed, statistically significant decrease in number and volume of the nuclei in calcitonin-secreting cells (C-cells) was especially pronounced during 4.5--9 h after landing. Similar but less pronounced changes were observed in C-cells of the rats subjected to artificial conditions of space flight, besides weightlessness. The similarity of the changes in the animals of both groups made it possible to connect the increasing amount of C-cells and the morphological symptoms of their functional inhibition with the effect of weightlessness and hypokinesia. During the space flight, the animals were kept under the conditions of artificial gravitation on board the biosatellite and therefore morphological peculiarities specific for the earth conditions were preserved in C-cells and the thyroid gland. Thus, it was concluded that artificial gravitation prevented the development of the thyroid changes which appeared under the influence of weightlessness.
在“宇宙-936”号太空生物卫星上进行了18.5天飞行后，于着陆后4.5 - 13小时及25天，对特定无病原体等级的Wistar大鼠的甲状腺进行了研究。在经历失重的动物中，观察到甲状腺功能减退的中度症状，降钙素分泌细胞（C细胞）的细胞核数量和体积在着陆后4.5 - 9小时有统计学意义的显著下降，这一现象尤为明显。除失重外，在经历模拟太空飞行人工条件的大鼠C细胞中也观察到了类似但不太明显的变化。两组动物变化的相似性使得将C细胞数量的增加及其功能抑制的形态学症状与失重和运动减少的影响联系起来成为可能。在太空飞行期间，动物被置于生物卫星上的人工重力条件下，因此C细胞和甲状腺中保留了特定于地球条件的形态学特征。因此，得出的结论是，人工重力阻止了在失重影响下出现的甲状腺变化的发展。
