Aertgeerts B, Buntinx F, Bande-Knops J, Vandermeulen C, Roelants M, Ansoms S, Fevery J
Department of General Practice, University Hospital Gasthuisberg, Catholic University of Leuven, Belgium.
Alcohol Clin Exp Res. 2000 Jan;24(1):53-7.
This study attempted to (1) determine the prevalence of alcohol problems in college freshmen, (2) assess the performance of both the CAGE and the Alcohol Use Disorders Identification Test (AUDIT) questionnaires in this population, and (3) assess the possibility of improving the CAGE and/or AUDIT.
A sample of 3564 consecutive college freshmen, with a mean age of 18 years, at the Catholic University of Leuven, (Belgium) completed, during a cross-sectional study, a questionnaire assessing drinking behavior and identifying students at risk as defined by DSM-IV criteria. The questionnaire also included the CAGE questionnaire and the AUDIT. Calculations of sensitivity, specificity, negative predictive value, positive predictive value, likelihood ratios, and receiver operating characteristic curves for different scores of the CAGE and the AUDIT were performed, using DSM-IV criteria as the reference standard.
The area under the receiver operating characteristic curve of the CAGE and the AUDIT was 0.76 and 0.85, respectively. The cutoff score of 1 for the CAGE was associated with a sensitivity of 42%, a specificity of 87%, a positive predictive value of 36%, and a negative predictive value of 90%. A score of 6 or more for the AUDIT gave a sensitivity of 80%, a specificity of 78%, a positive predictive value of 37%, and a negative predictive value of 77%. These results were related with a prevalence of 14.1% of alcohol problems. Replacing one question of the CAGE by "often driving under the influence" resulted in the CUGE (acronym for "cut down, under influence, guilty feelings, and eye opener"), with an area under the curve of 0.96, a positive likelihood ratio of 8.7, and a negative likelihood ratio of 0.04.
Prevalence of alcohol problems in college students is confirmed to be high. When screening for alcohol problems in a college freshmen population, one question seems extremely important. The newly constructed CUGE questionnaire may improve screening efforts in students, compared with existing questionnaires.
本研究旨在(1)确定大学新生中酒精问题的患病率,(2)评估CAGE问卷和酒精使用障碍识别测试(AUDIT)问卷在该人群中的表现,以及(3)评估改进CAGE问卷和/或AUDIT问卷的可能性。
在比利时鲁汶天主教大学,对3564名连续入学的大学新生进行了一项横断面研究,这些新生的平均年龄为18岁。他们完成了一份评估饮酒行为并根据《精神疾病诊断与统计手册》第四版(DSM-IV)标准识别有风险学生的问卷。该问卷还包括CAGE问卷和AUDIT问卷。以DSM-IV标准作为参考标准,对CAGE问卷和AUDIT问卷不同分数的敏感性、特异性、阴性预测值、阳性预测值、似然比和受试者工作特征曲线进行了计算。
CAGE问卷和AUDIT问卷的受试者工作特征曲线下面积分别为0.76和0.85。CAGE问卷的临界值为1时,敏感性为42%,特异性为87%,阳性预测值为36%,阴性预测值为90%。AUDIT问卷得分6分及以上时,敏感性为80%,特异性为78%,阳性预测值为37%,阴性预测值为77%。这些结果与14.1%的酒精问题患病率相关。用“经常酒后驾车”替换CAGE问卷中的一个问题后得到了CUGE(“减少饮酒、受影响、有负罪感和睁眼问题”的首字母缩写),其曲线下面积为0.96,阳性似然比为8.7,阴性似然比为0.04。
大学生中酒精问题的患病率确实很高。在大学新生人群中筛查酒精问题时,有一个问题似乎极其重要。与现有问卷相比,新构建的CUGE问卷可能会改善对学生的筛查工作。