Leggiadro R J
Department of Pediatrics, Sisters of Charity Medical Center, Staten Island, New York 10310, USA.
Infect Control Hosp Epidemiol. 2000 Jan;21(1):53-6. doi: 10.1086/501700.
Bioterrorism is an emerging public health and infection control threat. Potential biological agents include smallpox, anthrax, plague, tularemia, botulinum toxin, brucellosis, Q fever, viral encephalitis, hemorrhagic fever, and staphylococcal enterotoxin B. An understanding of the epidemiology, clinical manifestations, and management of the more likely candidate agents is critical to limiting morbidity and mortality from a biological event. Effective response requires an increased index of suspicion for unusual diseases or syndromes, with prompt reporting to health authorities to facilitate recognition of an outbreak and subsequent intervention. Hospital epidemiology programs will play a crucial role in this effort.
生物恐怖主义是一种新出现的公共卫生和感染控制威胁。潜在的生物制剂包括天花、炭疽、鼠疫、兔热病、肉毒杆菌毒素、布鲁氏菌病、Q热、病毒性脑炎、出血热和葡萄球菌肠毒素B。了解更有可能的候选制剂的流行病学、临床表现和管理对于限制生物事件导致的发病率和死亡率至关重要。有效的应对需要提高对不寻常疾病或综合征的怀疑指数，并及时向卫生当局报告，以便于识别疫情并随后进行干预。医院流行病学项目将在这项工作中发挥关键作用。
