无症状成年受试者的脑电图
Electroencephalogram of asymptomatic adult subjects.
作者信息
Jabbari B, Russo M B, Russo M L
机构信息
Department of Neurology, Uniformed Services University of Health Sciences, Bethesda, MD 20814, USA.
出版信息
Clin Neurophysiol. 2000 Jan;111(1):102-5. doi: 10.1016/s1388-2457(99)00189-3.
OBJECTIVES
The objective of this study is to investigate the incidence of epileptiform activity, focal or generalized slowing, patterns of uncertain significance and the effects of hyperventilation, photic stimulation and sleep on the electroencephalogram of asymptomatic adult subjects.
METHODS
The studied group consisted of 100 male subjects with a mean age of 34 years (range 18-45 years). Each subject was screened closely for personal or family history of seizures, HIV, head trauma and drug abuse. Half of the subjects had a magnetic resonance imaging scan (MRI).
RESULTS
In no subject resting or activated EEG showed any epileptiform activity or excessive slowing (focal or generalized). One subject demonstrated an H-response, one disclosed an alpha asymmetry of more than 50% and one showed slow alpha variant. Fourteen and 6 positive burst (12%) and small sharp spikes (11%) were the two most common patterns of uncertain significance.
CONCLUSION
In a carefully screened population of young and middle age adults, the incidence of epileptiform activity, photoparoxysmal response or excessive slowing is less than 1%.
目的
本研究的目的是调查无症状成年受试者脑电图中癫痫样活动、局灶性或广泛性慢波、意义不确定的模式以及过度换气、光刺激和睡眠对脑电图的影响。
方法
研究组由100名男性受试者组成，平均年龄34岁（范围18 - 45岁）。对每位受试者进行密切筛查，了解其癫痫发作、HIV、头部外伤和药物滥用的个人或家族史。一半受试者进行了磁共振成像扫描（MRI）。
结果
在任何受试者的静息或激活脑电图中均未显示任何癫痫样活动或过度慢波（局灶性或广泛性）。一名受试者表现出H反应，一名受试者显示α不对称超过50%，一名受试者表现出慢α变异。14次阳性爆发（12%）和小棘波（11%）是两种最常见的意义不确定模式。
结论
在经过仔细筛查的中青年成年人中，癫痫样活动、光阵发性反应或过度慢波的发生率低于1%。
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