The Cold Spring Harbor Laboratory meeting on tyrosine phosphorylation and cell signaling. Cold Spring Harbor, NY, USA, May 12-16, 1999.

作者信息

Roussel M F

机构信息

Department of Tumor Cell Biology, Danny Thomas Research Tower, D5006C, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105-2794, USA.

出版信息

Biochim Biophys Acta. 2000 Feb 14;1470(1):R17-20. doi: 10.1016/s0304-419x(99)00035-9.

DOI:10.1016/s0304-419x(99)00035-9

PMID:10656991

Abstract

摘要

相似文献

The Cold Spring Harbor Laboratory meeting on tyrosine phosphorylation and cell signaling. Cold Spring Harbor, NY, USA, May 12-16, 1999.

Biochim Biophys Acta. 2000 Feb 14;1470(1):R17-20. doi: 10.1016/s0304-419x(99)00035-9.

Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.胰岛素生成细胞中Shb SH2结构域蛋白的过表达会导致通过IRS-1和IRS-2蛋白的信号传导发生改变。

Mol Med. 2002 Nov;8(11):695-704.

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.PTEN肿瘤抑制蛋白：磷脂酰肌醇3激酶信号传导的拮抗剂。

Biochim Biophys Acta. 2000 Feb 14;1470(1):M21-35. doi: 10.1016/s0304-419x(99)00032-3.

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.Src家族蛋白酪氨酸激酶改变PTEN的功能以调节磷脂酰肌醇3激酶/AKT级联反应。

J Biol Chem. 2003 Oct 10;278(41):40057-66. doi: 10.1074/jbc.M303621200. Epub 2003 Jul 17.

Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways.肿瘤抑制因子PTEN可抑制整合素和生长因子介导的丝裂原活化蛋白（MAP）激酶信号通路。

J Cell Biol. 1998 Nov 30;143(5):1375-83. doi: 10.1083/jcb.143.5.1375.

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation.Jurkat T细胞中PTEN的缺失导致Itk持续定位于质膜，并对CD3刺激产生高反应性。

Mol Cell Biol. 2000 Sep;20(18):6945-57. doi: 10.1128/MCB.20.18.6945-6957.2000.

CSF-1 signal transduction.集落刺激因子-1信号转导

J Leukoc Biol. 1997 Aug;62(2):145-55. doi: 10.1002/jlb.62.2.145.

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.磷脂酰肌醇3-激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白信号通路通过胰岛素受体底物-1介导且PTEN拮抗肿瘤坏死因子对胰岛素信号传导的抑制作用。

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4640-5. doi: 10.1073/pnas.051042298. Epub 2001 Apr 3.

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors.SHIP-1在T淋巴细胞中参与磷脂酰肌醇3,4,5-三磷酸代谢并可调节新型磷酸肌醇3-激酶效应器的证据。

J Immunol. 2002 Nov 15;169(10):5441-50. doi: 10.4049/jimmunol.169.10.5441.

PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells.PTEN可抑制PI3K/Akt信号通路，并诱导骨髓瘤细胞的生长抑制和凋亡，而SHIP和SHIP2则无此作用。

Oncogene. 2002 Aug 8;21(34):5289-300. doi: 10.1038/sj.onc.1205650.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验