Brannon R B
Oral Surg Oral Med Oral Pathol. 1976 Jul;42(1):54-72. doi: 10.1016/0030-4220(76)90031-1.
An analysis was made of the clinical features of 312 acceptable cases of odontogenic keratocysts from the files of the Department of Oral Pathology, Indiana University School of Dentistry. A total of 5.1 per cent of the keratocysts were from patients with the basal-cell nevus syndrome and 5.8 per cent were from patients with multiple keratocysts but with no other features of the syndrome. There was a wide age range, with a peak incidence in the second and third decades of life. The mandible: maxilla ratio was 2:1, with the mandibular third molar area and ramus being the most common sites. Dentigerous cyst was the most frequent clinical as well as histologic diagnosis for the majority of the keratocysts in this study. The primordial cyst comprised the greatest percentage of keratocysts (44.4 per cent). A total of 50.3 per cent of the patients were symptomatic before seeking treatment, the most common finding being intraoral drainage and swelling. Their radiographic appearance was quite variable, although they frequently resembled ameloblastoma. These cysts may be very aggressive clinically. They have a relatively high recurrence rate, as previously reported in the literature, in comparison with other types of odontogenic cyst. The findings in this study support the theory that the histologic appearance of an odontogenic keratocyst may be assumed by any of the odontogenic or nonodontogenic cysts.
对印第安纳大学牙科学院口腔病理科档案中的312例可接受的牙源性角化囊肿病例的临床特征进行了分析。共有5.1%的角化囊肿来自基底细胞痣综合征患者，5.8%来自患有多发性角化囊肿但无该综合征其他特征的患者。年龄范围广泛，发病高峰在第二和第三个十年。下颌骨与上颌骨的比例为2:1，下颌第三磨牙区和下颌支是最常见的部位。在本研究中，多数角化囊肿的临床及组织学诊断均为含牙囊肿。原始囊肿占角化囊肿的比例最大（44.4%）。共有50.3%的患者在寻求治疗前有症状，最常见的表现是口腔内引流和肿胀。其影像学表现差异很大，尽管它们常常类似成釉细胞瘤。这些囊肿在临床上可能具有很强的侵袭性。与其他类型的牙源性囊肿相比，它们的复发率相对较高，如先前文献报道。本研究结果支持以下理论，即任何牙源性或非牙源性囊肿都可能呈现出牙源性角化囊肿的组织学表现。
