Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Mumbai, India.
Sultan Qaboos Univ Med J. 2023 Aug;23(3):288-296. doi: 10.18295/squmj.5.2023.021. Epub 2023 Aug 28.
Papilliferous keratoameloblastoma (PKA) is a rare entity, and not much is known about its clinicodemographic features or biological nature. This review aimed to provide clarity regarding the characterisation of the demographic, clinical, radiological and histopathological features of PKA. Case reports of PKA were identified through a systematic search across multiple databases. The search yielded a total of 10 cases, half of which were of Indian origin. All the cases invariably occurred in the mandibular posterior region and involved the right side; only one case primarily involved the left side of the mandible. PKA should be considered a variant of the conventional ameloblastoma that is towards the more aggressive end of the spectrum. It tends to occur in older individuals (in their fifth decade or older), with a marked propensity to occur in the right mandibular posterior region. Surgical resection with diligent follow-up is warranted in the treatment of PKA.
乳头状角化性成釉细胞瘤（PKA）较为罕见，其临床和组织学特征及生物学行为尚不完全清楚。本研究旨在明确 PKA 的临床、影像学和组织病理学特征。通过对多个数据库进行系统检索，共发现 10 例 PKA 病例报告，其中一半来自印度。所有病例均发生在下颌后区，右侧多见，仅 1 例原发于下颌左侧。PKA 被认为是传统成釉细胞瘤的一种变异型，具有侵袭性。其好发于年龄较大者（50 岁以上），尤其是右侧下颌后区。手术切除后密切随访是治疗 PKA 的必要手段。
