Kushwaha A C, Whitman G J, Stelling C B, Cristofanilli M, Buzdar A U
Division of Diagnostic Imaging, The University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
AJR Am J Roentgenol. 2000 Feb;174(2):535-8. doi: 10.2214/ajr.174.2.1740535.
Our goal was to describe the mammographic characteristics of primary inflammatory carcinoma of the breast.
We identified the medical records of 43 women who participated in a chemotherapy protocol for primary inflammatory carcinoma of the breast between 1994 and 1997. Mammograms were available for review in 26 women (age range, 34-78 years; mean age, 56 years). Two radiologists independently reviewed the 26 mammograms obtained before patients underwent treatment. A third observer was the final arbiter when needed.
Mammographic findings included skin thickening in 24 patients (92%), diffusely increased density in 21 patients (81%), trabecular thickening in 16 patients (62%), axillary lymphadenopathy in 15 patients (58%), architectural distortion or focal asymmetric density in 13 patients (50%), and nipple retraction in 10 patients (38%). Malignant-appearing calcifications were seen in six patients (23%), and a mass was seen in four patients (15%).
Diffuse mammographic abnormalities such as skin thickening, increased density, trabecular thickening, and axillary lymphadenopathy are common at presentation in patients with primary inflammatory carcinoma of the breast. Mammographic masses and malignant-appearing calcifications are uncommon manifestations of this disease.
我们的目标是描述原发性乳腺炎性癌的乳房X线特征。
我们确定了1994年至1997年间参与原发性乳腺炎性癌化疗方案的43名女性的病历。26名女性（年龄范围34 - 78岁；平均年龄56岁）有乳房X线照片可供复查。两名放射科医生独立复查了患者治疗前获得的26张乳房X线照片。必要时，第三名观察者为最终裁决者。
乳房X线表现包括24例（92%）皮肤增厚、21例（81%）弥漫性密度增加、16例（62%）小梁增厚、15例（58%）腋窝淋巴结肿大、13例（50%）结构扭曲或局灶性不对称密度以及10例（38%）乳头回缩。6例（23%）可见恶性钙化，4例（15%）可见肿块。
乳房X线弥漫性异常，如皮肤增厚、密度增加、小梁增厚和腋窝淋巴结肿大，在原发性乳腺炎性癌患者就诊时很常见。乳房X线肿块和恶性钙化是该疾病的少见表现。
