Yong R, Karas T J, Smith K D, Petrov O
Catholic Health Partners Podiatric Residency Program, Chicago, IL, USA.
J Foot Ankle Surg. 2000 Jan-Feb;39(1):34-8. doi: 10.1016/s1067-2516(00)80061-7.
Peripheral neuropathy is a risk factor that predisposes diabetic patients to plantar foot ulcerations and lower extremity amputations. Clinicians have searched for a reliable, cost-effective, and simple method in the identification of diabetic patients who are at increased risk of developing plantar foot ulcers. Currently, many diabetic foot clinics utilize the Semmes-Weinstein 5.07/10 g monofilament in this identification process. Ten 5.07 monofilaments were placed in an Instron Dynamic Testing Instrument and their respective filament forces were measured utilizing a Mettler scale after being subjected to repetitive applications. After 500 cycles were performed, there was an average filament force reduction of 1.2 g. After 1,500 cycles, there was still an average reduction of 1.2 g. F-testing and the Duncan test identified a significant difference between filament forces at 0, 500, 1,000, and 1,500 cycles. These data lead to a conclusion that continual utilization of the nylon filaments may lead to a reduced ability to accurately detect peripheral neuropathy and identify those who are at risk for the development of plantar foot ulcerations.
周围神经病变是糖尿病患者发生足底溃疡和下肢截肢的一个危险因素。临床医生一直在寻找一种可靠、经济有效且简单的方法来识别发生足底溃疡风险增加的糖尿病患者。目前，许多糖尿病足诊所在此识别过程中使用Semmes-Weinstein 5.07/10 g单丝。将十根5.07单丝置于英斯特朗动态测试仪器中，并在经过重复使用后，使用梅特勒天平测量其各自的丝力。在进行500次循环后，丝力平均降低了1.2 g。在进行1500次循环后，平均仍降低1.2 g。F检验和邓肯检验确定了在0、500、1000和1500次循环时丝力之间存在显著差异。这些数据得出一个结论，即持续使用尼龙丝可能会导致准确检测周围神经病变以及识别有发生足底溃疡风险者的能力下降。
