Harris J E, Draper H L, Rhodes A I, Stevens J M
Department of Diagnostic Radiology, St Mary's Hospital, London.
J Accid Emerg Med. 2000 Jan;17(1):15-7. doi: 10.1136/emj.17.1.15.
A recent American study identified clinical factors which effectively predicted those patients who would have significant findings on cranial computed tomography. It was proposed to apply these criteria in a UK setting and to determine whether modifications could be made to improve their efficiency.
A prospective observational study was conducted over a four month period including all non-trauma adult patients referred from the accident and emergency (A&E) department for urgent cranial computed tomography. Presenting symptoms and signs were analysed for ability to predict clinically significant computed tomography findings, namely: acute infarct, malignancy, acute hydrocephalus, intracranial haemorrhage, or intracranial infection.
Sixty two patients were included; 22 (35%) had significant findings on computed tomography. Applying the original criteria (any of: age 60 years or older, focal neurology, headache with nausea or vomiting, altered mental status) to the study population showed that no clinically significant tomograms would have been omitted but only 11% fewer performed. Modifying the criteria by removing "age 60 years or older" and replacing "altered mental status" with a Glasgow coma score <14, still ensured 100% sensitivity and would have resulted in 19% fewer scans being performed.
Simple clinical criteria can be usefully applied to patients presenting to an A&E department in this country to target patients most likely to have clinically significant findings on urgent cranial computed tomography.
最近一项美国研究确定了一些临床因素,这些因素能有效预测哪些患者在头颅计算机断层扫描(CT)上会有显著发现。有人提议在英国应用这些标准,并确定是否可以进行修改以提高其效率。
进行了一项为期四个月的前瞻性观察研究,纳入了所有从急诊部门转诊进行紧急头颅CT检查的非创伤成年患者。分析了患者的症状和体征,以评估其预测CT显著发现的能力,这些发现包括:急性梗死、恶性肿瘤、急性脑积水、颅内出血或颅内感染。
共纳入62例患者;22例(35%)在CT上有显著发现。将原始标准(年龄60岁及以上、局灶性神经功能缺损、伴有恶心或呕吐的头痛、意识状态改变中的任何一项)应用于研究人群,结果显示不会遗漏任何具有临床意义的CT图像,但检查数量仅减少了11%。通过去除“年龄60岁及以上”并将“意识状态改变”替换为格拉斯哥昏迷评分<14来修改标准,仍可确保100%的敏感性,并且扫描次数将减少19%。
简单的临床标准可有效地应用于本国急诊部门的患者,以确定哪些患者最有可能在紧急头颅CT检查中出现具有临床意义的发现。