Savastio G, Golfieri R, Pastore Trossello M, Venturoli L
Radiodiagnostica d'Urgenza, Policlinico S. Orsola, Bologna.
Radiol Med. 1991 Dec;82(6):769-75.
A prospective study was performed on 4,262 consecutive patients who had had skull examinations for recent head trauma. Clinical signs and symptoms and patient history were correlated with skull fractures and intracranial sequelae as identified on CT studies, in order to evaluate the predictive value of each clinical finding and to identify high-yield referral criteria. Ninety-seven skull fractures (3%) and 32 intracranial sequelae (0.7%) were observed. All the intracranial complications were observed in patients with fractures and with altered consciousness of some degrees (Glasgow Coma Scale score less than 13). Most patients were asymptomatic (41%) or showed "low risk" symptoms (29%): among them, neither fractures nor complications were observed. High-risk clinical signs, mainly expressing basilar fractures (as rhinorrhea, otorrhea, focal neurologic signs, retroauricular hematoma) demonstrated high predictive value (100%) for intracranial sequelae. Other "moderate risk" findings for intracranial injury--i.e. loss of consciousness at any time, antegrade or retrograde amnesia, multiple trauma, and possible skull penetration--showed a high correlation with skull fractures and a slightly lower one with intracranial sequelae. The most predictive finding for brain injury was the depressed level of consciousness: brain injuries were never observed in fully conscious patients; in altered consciousness with GCS 15-13 we observed 4% of skull fractures with no sequelae; at GCS values 12-9, 61% of skull fractures and 20% of sequelae were present, whereas at GCS less than 8, 100% of complicated fracture were observed. The finding of skull fracture showed 33% of predictivity for brain damage, which was, however, always associated with "high or moderate risk" clinical signs. Therefore, the authors suggest some guidelines for the management of patients with recent head trauma, including referral criteria for X-rays or CT studies, based on signs and symptoms with high, intermediate and low risk of developing intracranial sequelae.
对4262例因近期头部外伤而接受颅骨检查的连续患者进行了一项前瞻性研究。将临床体征、症状及患者病史与CT检查所发现的颅骨骨折及颅内后遗症进行关联分析,以评估各项临床发现的预测价值,并确定高收益的转诊标准。共观察到97例颅骨骨折(3%)和32例颅内后遗症(0.7%)。所有颅内并发症均见于骨折且伴有不同程度意识改变(格拉斯哥昏迷量表评分低于13分)的患者。大多数患者无症状(41%)或表现出“低风险”症状(29%):在这些患者中,未观察到骨折或并发症。主要提示颅底骨折的高风险临床体征(如鼻漏、耳漏、局灶性神经体征、耳后血肿)对颅内后遗症具有较高的预测价值(100%)。其他颅内损伤的“中度风险”表现——即任何时候的意识丧失、顺行或逆行性遗忘、多发伤以及可能的颅骨穿透——与颅骨骨折高度相关,与颅内后遗症的相关性略低。对脑损伤最具预测性的表现是意识水平降低:意识完全清醒的患者从未观察到脑损伤;意识改变且格拉斯哥昏迷量表评分为15 - 13分的患者中,4%有颅骨骨折但无后遗症;格拉斯哥昏迷量表评分为12 - 9分的患者中,61%有颅骨骨折,20%有后遗症,而格拉斯哥昏迷量表评分低于8分的患者中,100%有复杂骨折。颅骨骨折的发现对脑损伤的预测率为33%,然而,这总是与“高或中度风险”的临床体征相关。因此,作者提出了一些近期头部外伤患者的管理指南,包括根据发生颅内后遗症的高、中、低风险体征和症状,制定X线或CT检查的转诊标准。