Christensen N J
Acta Med Scand Suppl. 1979;624:9-18. doi: 10.1111/j.0954-6820.1979.tb00712.x.
The sympathetic nervous system is of major importance for the regulation of several physiological functions. Drugs which inhibit the actions of catecholamines and adrenergic drugs are used in the treatment of many clinical disorders. The potential role of catecholamines in a number of human diseases has, however, until recent years been studied to a limited extent only due to lack of methods for quantitation of sympathetic nervous activity. After the development of enzymatic isotope-derivative assays, reliable measurements of noradrenaline and adrenaline in plasma became available. Studies in man have shown that plasma noradrenaline is an index of sympathetic nervous activity. The present survey deals with sympathetic nervous activity and plasma adrenaline in a number of clinical disorders viz. arterial hypertension, duodenal ulcer, thyrotoxicosis, diabetes mellitus and ketotic hypoglycemia.
交感神经系统对多种生理功能的调节至关重要。抑制儿茶酚胺作用的药物和肾上腺素能药物被用于治疗许多临床疾病。然而，由于缺乏定量交感神经活动的方法，直到近年来，儿茶酚胺在多种人类疾病中的潜在作用仅得到了有限的研究。在酶促同位素衍生测定法发展之后，血浆中去甲肾上腺素和肾上腺素的可靠测量方法得以问世。对人类的研究表明，血浆去甲肾上腺素是交感神经活动的一个指标。本综述探讨了多种临床疾病中的交感神经活动和血浆肾上腺素，即动脉高血压、十二指肠溃疡、甲状腺毒症、糖尿病和酮症性低血糖。
