Jain S, Das D K, Malhotra V, Tatke M, Kumar N
Department of Pathology, Maulana Azad Medical College, New Delhi, India.
Acta Cytol. 2000 Jan-Feb;44(1):63-6. doi: 10.1159/000326227.
Cytomorphologic and ultrastructural features of molluscum contagiosum, a rare skin lesion of viral etiology, are presented.
A 4-month-old female was referred for fine needle aspiration cytology of papules over the back and chest wall. A Giemsa-stained preparation of whitish material aspirated from the chest wall nodule showed numerous large, intracytoplasmic, basophilic bodies that pushed the host cell nucleus to the periphery, giving a signet-ring appearance to a few cells. A cytologic diagnosis of molluscum contagiosum was suggested. On electron microscopy numerous intracytoplasmic viral particles were demonstrated, thus confirming the cytologic diagnosis.
In clinically unsuspected cases, the cytologic diagnosis of molluscum contagiosum can be suggested by demonstrating pathognomonic molluscum bodies in aspirated material.
介绍了传染性软疣这种罕见的病毒病因性皮肤病变的细胞形态学和超微结构特征。
一名4个月大的女性因背部和胸壁丘疹的细针穿刺细胞学检查前来就诊。从胸壁结节吸出的白色物质经吉姆萨染色制片显示有许多大的、胞质内嗜碱性小体，这些小体将宿主细胞核推向周边，使一些细胞呈现印戒样外观。提示传染性软疣的细胞学诊断。电子显微镜检查证实吸出物中有大量胞质内病毒颗粒，从而确诊了细胞学诊断。
在临床未怀疑的病例中，通过在吸出物中发现特征性的软疣小体可提示传染性软疣的细胞学诊断。
