Potts M
School of Public Health, University of California, Berkeley, USA.
Am J Public Health. 2000 Feb;90(2):188-90. doi: 10.2105/ajph.90.2.188.
A vaginal microbicide could slow the spread of HIV. To date, volunteers in placebo-controlled trials of candidate microbicides have been counseled to use condoms. This does not reduce the number of volunteers exposed to possible risk, but it shifts the allotment of risk from those conducting the trial to those women who may be least able to make autonomous decisions. Alternative ways of meeting the obligation to offer volunteers active benefits are explored. Counseling the use of condoms prolongs clinical trials and could cause tens of thousands of otherwise avoidable deaths.
一种阴道杀微生物剂可能会减缓艾滋病毒的传播。迄今为止，在候选杀微生物剂的安慰剂对照试验中，已建议志愿者使用避孕套。这并没有减少面临潜在风险的志愿者数量，而是将风险分配从进行试验的人转移到了那些可能最无法自主做决定的女性身上。人们探索了履行向志愿者提供积极益处义务的其他方式。建议使用避孕套会延长临床试验时间，并可能导致数万人死于原本可以避免的情况。
