Ricke J, Sehouli J, Hosten N, Stroszczynski C, Amthauer H, Rieger J, Buchmann E, Felix R
Strahlenklinik und Poliklinik, Charité Virchow-Klinikum, Medizinische Fakultät, Humboldt-Universität zu Berlin.
Rofo. 1999 Dec;171(6):461-7. doi: 10.1055/s-1999-270.
To evaluate contrast-enhanced, fat-saturated spin echo sequences for the detection of peritoneal carcinosis with MRI.
61 patients, 35 with and 26 without peritoneal carcinosis, were examined with abdominal MRI. Fat-saturated, T1-weighted spin echo sequences were performed before and after administration of Gd-DTPA. In addition, 22 patients with peritoneal carcinosis were examined with contrast-enhanced abdominal CT.
32 of 35 patients with peritoneal carcinosis demonstrated contrast enhancement of the visceral and 30 of 35 enhancement of the parietal peritoneum (91 and 86%, respectively). Wall thickening of the intestine or parietal peritoneum were noted in 21 and 20 of 35 patients (60 and 57%, respectively), ascites in 18 of 35 patients (51%). False positive contrast enhancement of the peritoneum was noted in 4 of 26 patients (15%). In the direct comparison of MRI and CT, 22 of 22 patients versus 7 of 22 patients showed contrast enhancement of the visceral peritoneum (100 and 32%, respectively). For other signs of peritoneal carcinosis (e.g., ascites, peritoneal seedings), no differences in diagnostic reliability were demonstrated.
The use of fat-saturated, spin echo sequences facilitates the diagnosis of peritoneal carcinosis by artifact reduction and improved detection of peritoneal contrast enhancement. MRI with fat-saturated sequences was superior to CT.
评估对比增强脂肪饱和自旋回波序列在磁共振成像(MRI)检测腹膜癌中的应用。
对61例患者进行腹部MRI检查,其中35例有腹膜癌,26例无腹膜癌。在静脉注射钆喷酸葡胺(Gd-DTPA)前后均行脂肪饱和T1加权自旋回波序列扫描。另外,对22例有腹膜癌的患者进行了对比增强腹部CT检查。
35例有腹膜癌的患者中,32例可见脏腹膜对比增强,30例可见壁腹膜对比增强(分别为91%和86%)。35例患者中,21例可见肠壁增厚,20例可见壁腹膜增厚(分别为60%和57%),18例有腹水(51%)。26例无腹膜癌的患者中,4例出现腹膜假阳性对比增强(15%)。在MRI与CT的直接对比中,22例有腹膜癌的患者中,22例可见脏腹膜对比增强,而CT检查的22例患者中只有7例可见(分别为100%和32%)。对于腹膜癌的其他征象(如腹水、腹膜种植),两者在诊断可靠性上无差异。
使用脂肪饱和自旋回波序列可减少伪影并提高腹膜对比增强的检出率,有助于腹膜癌的诊断。脂肪饱和序列的MRI优于CT。