Tocchi A, Mazzoni G, Liotta G, Costa G, Lepre L, Miccini M, De Masi E, Lamazza M A, Fiori E
First Department of Surgery, University of Rome La Sapienza, Italy.
Arch Surg. 2000 Feb;135(2):153-7. doi: 10.1001/archsurg.135.2.153.
Although advances in endoscopic procedures have provided alternative options for relieving biliary obstructions, the overall chance of cure for patients with benign biliary stricture is the same using surgical or endoscopic treatment.
Case-control study.
Tertiary care university hospital.
Of 163 patients referred for treatment with diagnoses of benign strictures of the common bile duct between January 1, 1975, and July 1, 1998, we studied 42 patients with postcholecystectomy stricture and a follow-up longer than 60 months. Twenty of these patients were treated with endoscopic stenting and 22 with surgery (hepaticojejunostomy, choledochojejunostomy, or intrahepatic cholangiojejunostomy).
Postoperative mortality and morbidity and long-term outcome. The rate of restenosis was also determined.
Morbidity occurred more frequently in patients treated with endoscopic procedures than with surgical ones (9 vs 2; P = .34). Hospital mortality was 0%. Surgery achieved excellent or good long-term outcome in 17 of 22 patients. Endoscopic biliary stenting was successful in 16 of 20 patients. Overall, excellent or good outcomes were achieved in 34 patients (81%).
The ability to achieve steady, long-term results confirms hepaticojejunostomy as the best procedure in the treatment of benign biliary strictures, even if endoscopic procedures are gaining a new role in the treatment of a greater number of patients.
尽管内镜手术的进展为缓解胆道梗阻提供了替代选择,但对于良性胆道狭窄患者,采用手术或内镜治疗的总体治愈机会相同。
病例对照研究。
三级医疗大学医院。
在1975年1月1日至1998年7月1日期间,163例被诊断为胆总管良性狭窄并转诊接受治疗的患者中,我们研究了42例胆囊切除术后狭窄且随访时间超过60个月的患者。其中20例患者接受内镜支架置入治疗,22例接受手术治疗(肝空肠吻合术、胆总管空肠吻合术或肝内胆管空肠吻合术)。
术后死亡率、发病率和长期结局。还确定了再狭窄率。
接受内镜手术的患者发病率高于接受手术的患者(9例 vs 2例;P = 0.34)。医院死亡率为0%。22例患者中有17例手术取得了优异或良好的长期结局。20例患者中有16例内镜胆道支架置入成功。总体而言,34例患者(81%)取得了优异或良好的结局。
获得稳定长期结果的能力证实肝空肠吻合术是治疗良性胆道狭窄的最佳手术方式,即使内镜手术在治疗更多患者方面正发挥新的作用。