Cosemans I, Zeyen P, Zeyen T
Middelheim Hospital, Department of Ophthalmology, Antwerp, Belgium.
Bull Soc Belge Ophtalmol. 1999;274:87-92.
To evaluate the protective effect of 1% sodium hyaluronate (Healon) vs. a mixture of 4% chondroitin sulfate and 3% sodium hyaluronate (Viscoat) on the central corneal endothelium during surgery, we prospectively examined 20 eyes of 20 patients who underwent clear corneal phacoemulsification and implantation of an intracapsular posterior chamber intraocular lens (PC-IOL) with either Healon (10 eyes) or a combined use of Viscoat and Healon (10 eyes) as viscoelastic material. We compared the central endothelial cell counts, recorded by specular microscopy, preoperatively and 6 weeks postoperatively. Our results suggest that Viscoat offers no significant better endothelial cell protection during phacoemulsification than Healon.
为评估1%透明质酸钠(Healon)与4%硫酸软骨素和3%透明质酸钠混合物(Viscoat)在手术期间对中央角膜内皮的保护作用,我们前瞻性地检查了20例患者的20只眼睛,这些患者接受了透明角膜超声乳化术并植入了囊袋内后房型人工晶状体(PC-IOL),其中10只眼睛使用Healon作为粘弹剂,另外10只眼睛联合使用Viscoat和Healon作为粘弹剂。我们比较了术前和术后6周通过镜面显微镜记录的中央内皮细胞计数。我们的结果表明,在超声乳化术中,Viscoat对内皮细胞的保护作用并不比Healon显著更好。