乳腺磁共振成像在确定乳腺为不明转移性淋巴结病来源中的作用。
Role of breast magnetic resonance imaging in determining breast as a source of unknown metastatic lymphadenopathy.
作者信息
Henry-Tillman R S, Harms S E, Westbrook K C, Korourian S, Klimberg V S
机构信息
Department of Surgery, University of Arkansas for Medical Sciences, John L. McClellan Veterans Administration Hospital, Little Rock 72205, USA.
出版信息
Am J Surg. 1999 Dec;178(6):496-500. doi: 10.1016/s0002-9610(99)00221-4.
BACKGROUND
Occult primary breast cancer (OPBC) represents less than 1% of breast cancer. In only a third of cases, mammography identifies a primary tumor. We hypothesized that rotating delivery of excitation off-resonance breast magnetic resonance imaging (MRI) would identify or exclude the breast as a primary site in patients with OPBC.
METHODS
In a retrospective review, 10 patients were identified with OPBC in which MRI was performed. Malignant appearing lesions were correlated with histopathologic findings at biopsy or surgery.
RESULTS
MRI identified the primary site in 8 of 10 cases as breast (80%), and excluded it in 2 cases. The extent of disease and location was accurately predicted when compared with histopathologic specimen.
CONCLUSIONS
As we continue to focus on a cure of early breast cancer, it is imperative that diagnostic images become more sensitive and specific. MRI accurately predicted OPBC in this subset of patients.
背景
隐匿性原发性乳腺癌（OPBC）占乳腺癌的比例不到1%。仅在三分之一的病例中，乳腺X线摄影能发现原发性肿瘤。我们推测，旋转激发失谐乳腺磁共振成像（MRI）能够识别或排除OPBC患者的乳腺作为原发部位。
方法
在一项回顾性研究中，确定了10例接受MRI检查的OPBC患者。将表现为恶性的病变与活检或手术时的组织病理学结果进行关联。
结果
MRI在10例病例中的8例（80%）确定原发部位为乳腺，并在2例中排除了乳腺。与组织病理学标本相比，疾病范围和位置得到了准确预测。
结论
随着我们继续专注于早期乳腺癌的治愈，诊断图像必须变得更加敏感和特异。MRI在这部分患者中准确预测了OPBC。
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