Kapp-Simon K A, Krueckeberg S
The Craniofacial Center of the University of Illinois at Chicago, USA.
Cleft Palate Craniofac J. 2000 Jan;37(1):65-70. doi: 10.1597/1545-1569_2000_037_0065_mdiiwc_2.3.co_2.
Investigated mental development in infants and toddlers with cleft lip and/or palate (CLP).
This was a retrospective analysis of developmental scores on qualified children between 4 and 36 months of age. Cross-sectional analysis included children in four age groups (6, 12, 18, and 24 months); longitudinal analysis included children at mean age 9.1 (range = 4 to 15) months at Time 1 and 24 months (range = 16 to 36) at Time 2.
Cross-sectional analysis included 180 children (59% male participants) in four diagnostic groups (cleft lip only [CL], cleft lip and palate [CLP], cleft palate only [CP], and Pierre Robin). The longitudinal sample included 85 children (64% male children) in the same diagnostic groups.
Mental Scale (MDI) of the Bayley Scales of Infant Development.
Mean MDIs were in the average range but decreased significantly between youngest and oldest groups in both cross-sectional (F(3,179) = 4.9, p<.01) and longitudinal samples (F(1,84) = 6.87, p<.01). There was a significant difference among cleft types (F(3,179) = 3.5, p<.025). Infants with CL obtained the highest scores, and infants with Pierre Robin Sequence obtained the lowest. Perceptual-motor development in the first year of life was predictive of developmental status at age 2.
The number of children with CLP who may be at risk for developmental problems during the second year of life is greater than would be expected. Children at greatest risk may demonstrate early delays in acquisition of perceptual-motor skills during the first year of life.
研究唇腭裂婴幼儿的心理发育情况。
这是一项对4至36个月合格儿童发育评分的回顾性分析。横断面分析包括四个年龄组（6、12、18和24个月）的儿童；纵向分析包括在时间1平均年龄为9.1（范围=4至15）个月且在时间2为24个月（范围=16至36）的儿童。
横断面分析包括四个诊断组（仅唇裂[CL]、唇腭裂[CLP]、仅腭裂[CP]和皮埃尔·罗宾序列）的180名儿童（59%为男性参与者）。纵向样本包括相同诊断组的85名儿童（64%为男性儿童）。
贝利婴幼儿发育量表的心理量表（MDI）。
平均MDI处于平均范围，但在横断面（F(3,179)=4.9，p<.01）和纵向样本（F(1,84)=6.87，p<.01）中最年幼组和最年长组之间均显著下降。腭裂类型之间存在显著差异（F(3,179)=3.5，p<.025）。CL患儿得分最高，皮埃尔·罗宾序列患儿得分最低。出生后第一年的感知运动发育可预测2岁时的发育状况。
在生命的第二年可能存在发育问题风险的唇腭裂儿童数量比预期的要多。风险最大的儿童可能在出生后第一年表现出感知运动技能获得方面的早期延迟。
