Hoffman T A, Damus A J, Sands L
Am J Clin Pathol. 1979 Feb;71(2):184-9. doi: 10.1093/ajcp/71.2.184.
The fluorescent gonorrhea test--heated (FGT-H), an indirect immunofluorescent method for detecting the presence of antigonococcal antibodies in serum, was evaluated in 1,000 women referred to a private clinic for the termination of pregnancy, 202 women treated at a municipal venereal disease clinic, and six women hospitalized with gonococcal bacteremia. The test was positive for 17.7% of private outpatients, even though gonococci were cultured from only 1.1% of these women, and another 5.1% had histories of gonococcal infection. Positive test results were found for 68.3% of the women in the venereal disease clinic population, in which the prevalence of gonococcal infection was 36.1% and an additional 25.2% had had gonorrhea previously. The test was positive for all six patients with gonococcemia. The sensitivity of the test in the low-risk population was 72.7%, which was not significantly different from the sensitivity of 84% in the high-risk population. Specificity of the test was 83% in low-risk patients, but only 41% in high-risk patients. These findings indicate that a negative test is a highly reliable means for excluding gonorrhea in populations of low-risk women. The predictive value of a positive test is low, ranging from 4.5% in the low-risk group to 45% in the high-risk group.
荧光淋病检测——加热法（FGT-H），一种用于检测血清中抗淋球菌抗体存在的间接免疫荧光法，在1000名到一家私人诊所进行人工流产的女性、202名在市性病诊所接受治疗的女性以及6名因淋球菌血症住院的女性中进行了评估。在私人门诊患者中，该检测的阳性率为17.7%，尽管这些女性中只有1.1%培养出淋球菌，另有5.1%有淋球菌感染史。在性病诊所的女性人群中，检测结果阳性率为68.3%，其中淋球菌感染患病率为36.1%，另有25.2%既往有淋病病史。所有6例淋球菌血症患者的检测结果均为阳性。该检测在低风险人群中的敏感性为72.7%，与高风险人群中84%的敏感性无显著差异。该检测在低风险患者中的特异性为83%，但在高风险患者中仅为41%。这些发现表明，检测结果为阴性是排除低风险女性人群中淋病的高度可靠方法。检测结果为阳性的预测价值较低，在低风险组为4.5%，在高风险组为45%。
