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直肠癌根治性系膜切除术后的膀胱及性功能障碍

Bladder and sexual dysfunction after mesorectal excision for rectal cancer.

作者信息

Nesbakken A, Nygaard K, Bull-Njaa T, Carlsen E, Eri L M

机构信息

Department of Surgery, Aker Hospital, Oslo, Norway.

出版信息

Br J Surg. 2000 Feb;87(2):206-10. doi: 10.1046/j.1365-2168.2000.01357.x.

Abstract

BACKGROUND

Urinary and sexual dysfunction are recognized complications of rectal excision for cancer. The aim of this study was to examine the frequency of such complications after mesorectal excision, shortly after this method was introduced.

METHODS

Spontaneous flowmetry, residual volume of urine measurement and urodynamic examination, including cystometry and simultaneous detrusor pressure and urinary flow recording, was carried out before and 3 months after curative rectal excision. Urinary symptoms and sexual function were evaluated by means of questionnaires before and after operation. Each patient served as his or her own control.

RESULTS

Forty-nine consecutive patients, 39 of whom had a total mesorectal excision (TME) and ten a partial mesorectal excision, were examined before surgery and 35 again after operation. In two patients, a weak detrusor was detected before operation. Two patients developed signs of bladder denervation after operation. Transitory moderate urinary incontinence appeared in four other women. Six of 24 men reported some reduction in erectile function and one became impotent. Two men reported retrograde ejaculation. All the complications were seen in the TME group.

CONCLUSION

Mesorectal excision for rectal cancer resulted in a low frequency of serious bladder and sexual dysfunction.

摘要

背景

泌尿和性功能障碍是直肠癌直肠切除术后公认的并发症。本研究的目的是在引入直肠系膜切除术后不久,检查该方法后此类并发症的发生频率。

方法

在根治性直肠切除术前及术后3个月进行自主尿流率测定、残余尿量测量及尿动力学检查,包括膀胱测压以及同步记录逼尿肌压力和尿流。通过问卷在手术前后评估泌尿症状和性功能。每位患者均作为自身对照。

结果

连续49例患者接受检查,其中39例行全直肠系膜切除术(TME),10例行部分直肠系膜切除术,术前检查,术后35例再次接受检查。2例患者术前检测出逼尿肌功能较弱。2例患者术后出现膀胱去神经支配迹象。另外4名女性出现短暂性中度尿失禁。24名男性中有6名报告勃起功能有所下降,1名出现阳痿。2名男性报告有逆行射精。所有并发症均出现在TME组。

结论

直肠癌直肠系膜切除术导致严重膀胱和性功能障碍的发生率较低。

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