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皮肤良性淋巴上皮瘤(“皮肤淋巴腺瘤”)

Benign lymphoepithelial tumor of the skin ("cutaneous lymphadenoma").

作者信息

Pujol R M, Matias-Guiu X, Taberner R, Alomar A

出版信息

Dermatol Online J. 1999 May;5(1):5.

PMID:10673448
Abstract

"Benign lymphoepithelial tumor of the skin" or "cutaneous lymphadenoma" is a distinctive benign adnexal tumor presenting a characteristic combination of lobules of epithelial basaloid cells with a peculiar histopathological pattern and a dense intraepithelial T-cell lymphoid and histiocytic population. We report an additional example of this peculiar neoplasm. In addition to the characteristic histopathological features, focal areas showing unequivocal follicular differentiation were observed at the periphery of the tumor. In agreement with other authors we consider that this neoplasm should be included within the spectrum of neoplasms of pilosebaceous origin. Nevertheless, we consider that the original and simple concept of "benign lymphoepithelial tumor of the skin" seems more suitable and illustrative than the more widely used term of "cutaneous lymphadenoma" to define this rare benign adnexal neoplasm.

摘要

“皮肤良性淋巴上皮瘤”或“皮肤淋巴腺瘤”是一种独特的良性附属器肿瘤,其呈现出上皮基底样细胞小叶的特征性组合,并伴有独特的组织病理学模式以及密集的上皮内T细胞淋巴样和组织细胞群体。我们报告了这一特殊肿瘤的又一病例。除了特征性的组织病理学特征外,在肿瘤周边还观察到明确显示毛囊分化的局灶性区域。与其他作者观点一致,我们认为该肿瘤应归入毛囊皮脂腺起源的肿瘤谱系。然而,我们认为“皮肤良性淋巴上皮瘤”这一原始且简单的概念,相较于更广泛使用的“皮肤淋巴腺瘤”一词,似乎更适合且更具说明性来定义这种罕见的良性附属器肿瘤。

相似文献

1
Benign lymphoepithelial tumor of the skin ("cutaneous lymphadenoma").皮肤良性淋巴上皮瘤(“皮肤淋巴腺瘤”)
Dermatol Online J. 1999 May;5(1):5.
2
[Lymphoepithelial tumor of the skin].[皮肤淋巴上皮瘤]
Arch Anat Cytol Pathol. 1998;46(3):199-203.
3
Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations.皮肤淋巴腺瘤是一种独特的具有毛母质细胞样特征的淋巴上皮肿瘤,具有弥漫性雄激素受体免疫反应性、Reed-Sternberg 样细胞中的 Notch1 配体以及常见的 EGFR 体细胞突变。
Am J Surg Pathol. 2021 Oct 1;45(10):1382-1390. doi: 10.1097/PAS.0000000000001727.
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Cutaneous lymphoepithelial neoplasms.
Adv Dermatol. 1997;12:277-94; discussion 295.
5
Cutaneous lymphadenoma: report of 2 cases.皮肤淋巴结瘤:2例报告。
Dermatology. 1992;185(1):62-5. doi: 10.1159/000247406.
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[A skin lymphoepithelial tumor (skin lymphadenoma)].[皮肤淋巴上皮瘤(皮肤淋巴结瘤)]
Acta Med Port. 1998 Jun;11(6):555-8.
7
A cutaneous adnexal neoplasm with features of adamantinoid trichoblastoma (lymphadenoma) in the benign component and lymphoepithelial-like carcinoma in the malignant component: a possible case of malignant transformation of a rare trichoblastoma variant.一种皮肤附属器肿瘤,其良性成分具有成釉细胞瘤样毛母细胞瘤(淋巴结瘤)特征,恶性成分具有淋巴上皮样癌特征:一种罕见毛母细胞瘤变体可能发生恶性转化的病例
Am J Dermatopathol. 2011 Oct;33(7):729-32. doi: 10.1097/DAD.0b013e31820b7b87.
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Glandular congenital lymphadenoma.腺性先天性淋巴结瘤
Pediatr Dermatol. 2007 Sep-Oct;24(5):547-50. doi: 10.1111/j.1525-1470.2007.00514.x.
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[Lympho-epithelial skin tumor. Case report with review of the literature and nosologic discussion].[淋巴上皮性皮肤肿瘤。病例报告并文献复习及疾病分类学讨论]
Ann Pathol. 1991;11(4):248-52.
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Cutaneous lymphadenoma.皮肤淋巴结瘤
J Eur Acad Dermatol Venereol. 2001 Sep;15(5):481-3. doi: 10.1046/j.1468-3083.2001.00302.x.

引用本文的文献

1
Cutaneous Lymphadenoma: A Case Report and Literature Review.皮肤淋巴结瘤:一例报告及文献综述
Clin Cosmet Investig Dermatol. 2023 Feb 23;16:505-514. doi: 10.2147/CCID.S378468. eCollection 2023.
2
Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations.皮肤淋巴腺瘤是一种独特的具有毛母质细胞样特征的淋巴上皮肿瘤,具有弥漫性雄激素受体免疫反应性、Reed-Sternberg 样细胞中的 Notch1 配体以及常见的 EGFR 体细胞突变。
Am J Surg Pathol. 2021 Oct 1;45(10):1382-1390. doi: 10.1097/PAS.0000000000001727.
3
Emerging treatments for noise-induced hearing loss.
噪声性听力损失的新兴治疗方法。
Expert Opin Emerg Drugs. 2011 Jun;16(2):235-45. doi: 10.1517/14728214.2011.552427. Epub 2011 Jan 20.