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[精神科环境中的多重耐药细菌]

[Multidrug resistant bacteria in a psychiatric milieu].

作者信息

Eveillard M, Manuel C, Gabastou J M, Caer M, Mounier M, Bourlioux P

机构信息

Laboratoire Central et Pharmacie, EPS Perray-Vaucluse, Epinay-Sur-Orge, France.

出版信息

Pathol Biol (Paris). 1999 Dec;47(10):1075-9.

Abstract

Isolation rates of multiple-drug resistant (MDR) bacteria were evaluated retrospectively in a psychiatric care facility. Over the six-year study period, 66 MDR bacterial strains were found. Methicillin-resistant Staphylococcus aureus contributed half of all MDR strains and 31% of all S. aureus strains. Among Pseudomonas aeruginosa strains, 22% were resistant to ticarcillin or imipenem, and among Enterobacteriaceae, 4.1% were MDR strains (production of a derepressed cephalosporinase or of an extended-spectrum beta-lactamase). Although most MDR strains were probably acquired during hospitalizations in short-term care facilities outside our institution, patient-to-patient transmission, either direct or via other individuals, cannot be ruled out. These data indicate that psychiatric care facilities should adopt the MDR strain monitoring strategies already used in other hospitals.

摘要

在一家精神科护理机构中,对多重耐药(MDR)细菌的分离率进行了回顾性评估。在为期六年的研究期间,共发现66株MDR细菌菌株。耐甲氧西林金黄色葡萄球菌占所有MDR菌株的一半,占所有金黄色葡萄球菌菌株的31%。在铜绿假单胞菌菌株中,22%对替卡西林或亚胺培南耐药,在肠杆菌科中,4.1%为MDR菌株(产生去阻遏头孢菌素酶或超广谱β-内酰胺酶)。尽管大多数MDR菌株可能是在本机构以外的短期护理机构住院期间获得的,但不能排除患者之间直接或通过其他个体的传播。这些数据表明,精神科护理机构应采用其他医院已经使用的MDR菌株监测策略。

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