Mouton C, Scheinin A, Mäkinen K K
Acta Odontol Scand. 1975;33(5):251-7. doi: 10.3109/00016357509004630.
The aim of the present study was to further investigate the plaque-reducing effect of a xylitol-containing chewing gum. Ninety-six dental students were divided randomly into three groups: a sucrose group (n = 32), a xylitol group (n = 36) and a control group (n = 28), using a sucrose-containing chewing gum, a xylitol-containing chewing gum, or no chewing gum, respectively, during a three-day experimental plaque growth period with restricted oral hygiene. The fresh weight of plaque collected in the xylitol group was 40% lower than in the sucrose group, along with a significantly lower mean plaque index. The use of the xylitol chewing gum induced low invertase-like activity in plaque extra-cellular phase together with low carbohydrate content. These results concur to indicate advantageous effects through the use of a xylitol-containing chewing gum.
本研究的目的是进一步探究含木糖醇口香糖的减少牙菌斑效果。96名牙科专业学生被随机分为三组：蔗糖组（n = 32）、木糖醇组（n = 36）和对照组（n = 28），在为期三天的实验性牙菌斑生长阶段，口腔卫生受限，分别使用含蔗糖口香糖、含木糖醇口香糖或不使用口香糖。木糖醇组收集的牙菌斑鲜重比蔗糖组低40%，同时平均菌斑指数也显著更低。使用木糖醇口香糖会使菌斑细胞外阶段的转化酶样活性降低，同时碳水化合物含量也降低。这些结果一致表明使用含木糖醇口香糖具有有益效果。
