Zhang W, Yu S, Zheng L
School of Stomatology, Beijing Medical University.
Zhonghua Kou Qiang Yi Xue Za Zhi. 1997 Jan;32(1):49-51.
The alveolar bone turnover in rat with experimental diabetes was investigated. The serum osteocalcin concentration in diabetic rat was shown to increase as determined by radioimmunoassay; while alveolar and femur bone density decrease as determined by Dual Energy X-ray Bone Densitometer; histological examination showed that bone resorption was increased and bone formation decreased in the alveolar bone in diabetic rat. It is suggested that the alveolar bone in rats with diabetes mellitus have a tendency to develop osteoporosis.
对实验性糖尿病大鼠的牙槽骨转换情况进行了研究。通过放射免疫测定法测定发现，糖尿病大鼠血清骨钙素浓度升高；而通过双能X线骨密度仪测定显示，牙槽骨和股骨骨密度降低；组织学检查表明，糖尿病大鼠牙槽骨的骨吸收增加而骨形成减少。提示糖尿病大鼠的牙槽骨有发生骨质疏松的倾向。
