Du B, Chen D, Liu D
Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Beijing.
Zhonghua Wai Ke Za Zhi. 1997 Jul;35(7):398-401.
To evaluate the incidence of central venous catheter-related sepsis (CRS) in critically ill patients, we performed a prospective study of the central venous catheters (CVCs) in ICU of the Peking Union Medical College Hospital from Jan. 1995 to March 1996. Of 151 CVCs, 13 (8.6%) had CRS, with an incidence of 16.7 episodes per 1000 catheter-days. Presence of infectious focus at catheterization, catheter insertion site, duration of catheterization, and the decrease of body temperature after catheter removal correlated with definite CRS, while difficulty of insertion, body temperature at catheter removal, as well as the decrease of body temperature after catheter removal correlated well with no CRS. The study showed that CRS is a serious problem in critically ill patients. Careful manipulation of CVCs is a major determinant in reducing the incidence of CRS.
为评估重症患者中心静脉导管相关败血症（CRS）的发生率，我们于1995年1月至1996年3月对北京协和医院重症监护病房（ICU）的中心静脉导管（CVC）进行了一项前瞻性研究。在151根CVC中，13根（8.6%）发生了CRS，每1000导管日的发生率为16.7次。置管时存在感染灶、导管插入部位、置管时间以及拔管后体温下降与明确的CRS相关，而插入困难、拔管时体温以及拔管后体温下降与无CRS相关性良好。该研究表明，CRS在重症患者中是一个严重问题。对CVC进行仔细操作是降低CRS发生率的主要决定因素。
