Franklin M S, Kraemer G W, Shelton S E, Baker E, Kalin N H, Uno H
Wisconsin Regional Primate Research Center, University of Wisconsin, Madison 53715-1299, USA.
Brain Res. 2000 Jan 10;852(2):263-7. doi: 10.1016/s0006-8993(99)02093-4.
While it has been established that the weight of the female rhesus monkey brain is less than that of the male, the sexual dimorphism of specific brain structures has not been well-documented. To further understand potential sex differences, we measured the whole brain volume and the size of the corpus callosum (mid-sagittal) and amygdala (largest coronal section) in MRI images from juvenile to adult male and female rhesus monkeys between 8 months and 7.2 years of age. The mean volume of the male brain was 89.2 +/- 1.9 (S.E.M.) compared to the female brain volume of 70.8 +/- 0.72 cm3. The average area of the corpus callosum increased from 8 months to 4.5 years; 0.56 to 0.93 cm2 in males and 0.45 to 0.66 cm2 in females. However, the average area of splenium is significantly greater in females (0.280 cm2), than males (0.184 cm2). The average area of the amygdala did not change with age; it was 1.07 +/- 0.037 (S.E.M.) in males and 1.08 +/- 0.022 cm2 in females. This data suggests that the whole brain volume and the size of the entire corpus callosum of young adult female rhesus monkeys are approximately 20% smaller than those of young adult males. Interestingly, the area of the splenial portion of the corpus callosum is larger in female monkeys. The size of the amygdala showed no sex difference.
虽然已经确定雌性恒河猴的脑重量小于雄性，但特定脑结构的性别二态性尚未得到充分记录。为了进一步了解潜在的性别差异，我们测量了8个月至7.2岁的幼年到成年雄性和雌性恒河猴MRI图像中的全脑体积以及胼胝体（矢状中切面）和杏仁核（最大冠状切面）的大小。雄性脑的平均体积为89.2±1.9（标准误），而雌性脑体积为70.8±0.72立方厘米。胼胝体的平均面积从8个月到4.5岁有所增加；雄性从0.56平方厘米增加到0.93平方厘米，雌性从0.45平方厘米增加到0.66平方厘米。然而，女性压部的平均面积（0.280平方厘米）显著大于男性（0.184平方厘米）。杏仁核的平均面积不随年龄变化；雄性为1.07±0.037（标准误），雌性为1.08±0.022平方厘米。这些数据表明，成年雌性恒河猴的全脑体积和整个胼胝体的大小比成年雄性大约小20%。有趣的是，雌性猴子胼胝体压部的面积更大。杏仁核的大小没有性别差异。
