Morand P, Bienvenu P, Masson D, Raynaud P, Amard M
Arch Mal Coeur Vaiss. 1978 Dec;71(12):1405-10.
The results of Isoprenaline stress tests, exercise electrocardiography and coronary arteriography were compared in 90 patients suspected of having coronary insufficiency. The technique used was a continuous intravenous infusion starting with an initial dosage of 3.8 gamma/minute and increasing progressively until the heart rate was equal to or greater than 130/minute, and sustained for three minutes. The same criteria of "positivity" were used as in the exercise test but only electrical charges which persisted or appeared 3 minutes after stopping the infusion were taken into consideration. In this series the sensitivity and specifity of the Isoprenaline test was greater than the exercise test if coronary arterial narrowing equal to or greater than 50% is considered significant. The prognostic values of positive tests which are classified in three groups according to the severity of the coronary artery disease, and the value of the isoprenaline test in the diagnosis of moderate single vessel disease are emphasised.
