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[术后停滞期儿童十二指肠细菌菌群]

[Duodenal bacterial flora in the child during post-surgical stasis].

作者信息

Ghnassia J C, Ricour C, Duhamel J F, Nihoul-Fékète C, Véron M

出版信息

Arch Fr Pediatr. 1978 Oct;35(8):854-62.

PMID:106800
Abstract

The bacterial flora of the small bowel was studied in infants with stasis after surgery. Samples were obtained, with radiological assistance, by duodenal aspiration and then immediately analysed by the laboratory in blind tests, both qualitatively and quantitatively. There were two groups of patients: one receiving parenteral nutrition and a second on enteral elementary diet; patients without any gastro-intestinal tract disease formed the control group. Pseudomonas aeruginosa and Enterobacteria were isolated significantly more often in both groups of patients compared to the control group. Quantitatively, the predominant flora -- and not total flora -- was different in the three groups. When considering bacteriological species, only P. aeruginosa (greater than 10(6)/ml) differed significantly in numbers in both groups compared to the control group. With these bacteriological investigations, the "contaminated proximal small bowel syndrome" is better defined and a group of high-risk patients may be identified.

摘要

对术后出现淤滞的婴儿小肠细菌菌群进行了研究。在放射学辅助下,通过十二指肠抽吸获取样本,然后实验室立即在盲法检测中对样本进行定性和定量分析。患者分为两组:一组接受肠外营养,另一组接受肠内要素饮食;无任何胃肠道疾病的患者组成对照组。与对照组相比,两组患者中铜绿假单胞菌和肠杆菌的分离频率明显更高。从数量上看,三组的主要菌群——而非总菌群——有所不同。在考虑细菌种类时,与对照组相比,仅两组中的铜绿假单胞菌(大于10⁶/ml)数量存在显著差异。通过这些细菌学研究,“近端小肠污染综合征”得到了更好的定义,并且可以识别出一组高危患者。

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