Weisgerber G, Lambert-Zechovsky N, Mandaba J L, Boureau M
Chir Pediatr. 1979;20(5):303-10.
This study is an evaluation of the infectious risk related to neonatal surgery in 300 patients between 1968 and 1978, and its consequences to mortality and morbidity. Bacteriological species, circumstances, chronology of infection, related to each type of surgical pathology prove the endogenous way of contamination to be usual and predominant. When intestinal obstruction occurs, the risk of hematogenous diffusion is directly dependent from local stasis and bacterial pullulation which can be evaulated with duodenal, jejunal or fecal samples. Both mechanical factors and antibiotictherapy can induce qualitative and quantitative changes in bacterial flora of the bowel, and then increase the incidence of endogenous septicemia.
本研究评估了1968年至1978年间300例新生儿手术的感染风险及其对死亡率和发病率的影响。与每种手术病理类型相关的细菌种类、感染情况及时间顺序证明,内源性污染途径是常见且主要的。当发生肠梗阻时,血行扩散的风险直接取决于局部淤滞和细菌繁殖,这可以通过十二指肠、空肠或粪便样本进行评估。机械因素和抗生素治疗均可引起肠道菌群的质和量的变化,进而增加内源性败血症的发生率。